| Metabolic engineering is the targeted improvement of the cellular metabolic phenotype using recombinant DNA technology. Experimental and mathematical techniques that are used to characterize metabolic networks are also included. Bioinformatics tools are critical for the advancement of metabolic engineering and many other fields in biotechnology. Abstracts describing new developments in these topics are sought, and those incorporating both mathematical modeling and experimental aspects are particularly encouraged. Example areas include quantification of metabolic fluxes, inverse metabolic engineering, production of novel products, application of evolutionary techniques, construction of metabolic models from genomic data, incorporation of microarray and proteomic data and mathematical modeling of metabolism. The session is open to papers focused on any type of organism. |
An Inverse Metabolic Engineering Approach For Tyrosine Production In Escherichia Coli
Christine Nicole S. Santos and Gregory Stephanopoulos, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139 |
Heterologous Production Of The Antimalarial Drug FR900098 In E. coli And Streptomyces lividans
Tyler Johannes, Chemical and Biomolecular Engineering, University of Illinois, 600 S Mathews, Box C-3 RAL 221 MC 712, Urbana, IL 61801 and Huimin Zhao, Chemical and Biomolecular Engineering, University of Illinois, 600 S Mathews, Box C-3 RAL 215 MC 712, Urbana, IL 61801 |
Metabolic Flux Elucidation For Large-Scale Models: 13C Labeled Isotope Analysis Of A Strain Of Escherichia coli Producing Amorphadiene
Patrick F. Suthers1, Anthony Burgard2, Farnaz Nowroozi3, Stephen Van Dien2, Jay D. Keasling4 and Costas D. Maranas5, (1)Department of Chemical Engineering, The Pennsylvania State University, 147 Fenske Lab, University Park, PA 16802, (2)Genomatica, Inc., 5405 Morehouse Drive, Suite 210, San Diego, CA 92121, (3)UC, Berkeley, 201 Gilman Hall, Berkeley, CA 94720-1462, (4)Chemical Engineering and Bioengineering, UC, Berkeley, 201 Gilman Hall, Berkeley, CA 94720-1462, (5)Department of Chemical Engineering, The Pennsylvania State University, University Park, PA 16802 |
Metabolic Engineering of Agrobacterium Sp. for Synthesis of Complex Carbohydrate Epitopes
Anne Ruffing, Zichao Mao and Rachel Ruizhen Chen, School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, Atlanta, GA 30332-0100 |
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Exploiting Phenotypic Diversity Through Global Transcription Machinery Engineering
Daniel Klein-Marcuschamer, Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave. 56-422, Cambridge, MA 02139 and Gregory Stephanopoulos, Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave. 56-469, Cambridge, MA 02139 |
Design, Construction, and Performance of A Carotenoid Over-Producing E. Coli
Pornkamol Unrean1, Cong Trinh1, Friedrich Srienc1 and Claudia Schmidt-Dannert2, (1)Chemical Engineering and Material Science/Biotechnology Institute, University of Minneasota, 1479 Gortner Avenue, Minneapolis/St. Paul, MN 55108, (2)Dept. Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN 612-625-5782 |
Overproduction Of Ohhl In E. Coli Via Directed Evolution And Metabolic Engineering
Lianhong Sun, Pavan Kumar Reddy Kambam and Daniel J. Sayut, Chemical Engineering, University of Massachusetts Amherst, 159 Goessmann Lab, 686 North Pleasant St, Amherst, MA 01003 |
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