Preliminary Program subject to change
15C10 Advances in Biocatalysis II
OverviewThis session focuses on engineering studies employing or enabling biocatalysis under non-biological conditions. The audience will be individuals from academia, government labs, and industry working to advance the usage of biocatalysis in all areas such as pharmaceuticals production, industrial processing and lignocellulose degradation. Talks will be sought to include both basic research studies and application examples thought to be beneficial to a wide biocatalysis audience. Possible examples include: stability engineering via selection or rational design, extremophile whole organism or pathway engineering, advances in process design, immobilization or regeneration, fundamental understanding of non-aqueous solvation effects in enzyme catalysis, advances in cofactor recycling, understanding of glycosylation effects on activity or secretion and methods to express active extreme enzymes in mesophilic hosts.
Primary SponsorBioengineering (15c)

Chair

Yi Tang
Chemical and BioMolecular Engineering
University of California, Los Angeles
420 Westwood Plaza
5331 Boelter Hall
Los Angeles, CA 90096
Phone Number: 310-825-0375
Fax Number: 310-206-4107
Email: yitang@seas.ucla.edu

CoChair

Louis A. Clark
Scientist
Codexis, Inc.
200 Penobscot drive
Redwood City, CA 94063
Phone Number: 650-298-5330
Email: louis.clark@codexis.com

CoChair

Patrick C. Cirino
Assistant Professor
Penn State University
120 Fenske Lab
University Park, PA 16802
Phone Number: 814-865-5790
Fax Number: 814-865-7846
Email: cirino@engr.psu.edu

* Membership Number 0000155622
Use of Hyperthermophilic Chaperones to Increase Survival Phenotypes in E. Coli
Shannon D. Chase1, Timothy Whitehead2, Pongpan Laksanalamai3, Anchalee Jiemjit3, Frank T. Robb3 and Douglas S. Clark4, (1)Chemical Engineering, UC Berkeley, 201 Gilman Hall #1462, Berkeley, CA 94720, (2)UC Berkeley, 201 Gilman Hall #1462, Berkeley, CA 94720, (3)University of Maryland, Center of Marine Biotechnology, Columbus Center, Suite 236, 701 East Pratt Street, Baltimore, MD 21202, (4)Chemical Engineering, University of California - Berkeley, Berkeley, CA 94720
Engineering E. Coli Whole-Cell Catalyst for Efficient Synthesis of Lactosyl Oligosaccharide
Zichao Mao1, Anne Ruffing2, Hyun-Dong Shin2, Jeong S. Oh1 and Rachel Ruizhen Chen3, (1)School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr. NW, Atlanta, GA 30332-0100, (2)Chemical and Biomolecular Engineering, Georgia Institute of Technology, 778 Atlantic Dr., Atlanta, GA 30332, (3)Chemical&Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive, NW, Atlanta, GA 30332-0100
Engineering E.Coli to Synthesize Simvastatin
Xinkai Xie, Chemical and Biomolecular, University of California at Los Angeles, 420 Westwood Plaza, 5667 Boelter Hall, Los Angeles, CA 90095 and Yi Tang, Chemical engineering, University of California at Los Angeles, 420 Westwood Plaza, 5667 Boelter Hall, Los Angeles, CA 90095
Increasing the in Vivo Availability of Reducing Equivalents by Metabolic Engineering in Escherichia Coli
Irene Martinez, Bioengineering, Rice University, 6100 Main Street MS 142, Houston, TX 77005, Jiangfeng Zhu, Department of Bioengineering, Rice University, Houston, TX 77005, Henry Lin, Department of Bioengineering, Rice University, 6100 Main St., MS 142, PO Box 1892, Houston, TX 77005, George N. Bennett, Biochemistry and Cell Biology, Rice University, 6100 Main Street MS#142, Houston, TX 77005 and Ka Yiu San, Department of Bioengineering, Department of Chemical and Biomolecular Engineering, Rice University, Houston, TX 77005
Modular Broad-Host-Range Expression Vectors for Heterologous Expression of Cytochrome P450 Genes in Bacteria
Jamie E. Prior1, Michael D Lynch1, Tobin Strom2, Uwe Christians2 and Ryan T Gill1, (1)Chemical Engineering, University of Colorado, 1111 Engineering Drive, Campus Box 424, Boulder, CO 80309, (2)University of Colorado, 1111 Engineering Drive, Campus Box 424, Boulder, CO 80309
Application of the Structure-Guided Consensus Concept for Increased Thermostability of Enzymes
Eduardo Vazquez-Figueroa, School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Dr, Atlanta, GA 30332, Javier Chaparro-Riggers, School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, IBB 3428, 315 Ferst Dr, Atlanta, GA 30332 and Andreas S. Bommarius, Georgia Institute of Technology, School of Chemical Engineering, 315 Ferst Drive N.W., Parker H. Petit Biotechnology Institute, Room 3310, Atlanta, GA 30332-0363

Food, Pharmaceutical & Bioengineering Division