Preliminary Program subject to change
T3011 Biomems and Microfluidics: Cell and Biomolecule Analysis
OverviewThe ability to study cellular processes at the single-cell level promises to provide a host of information with benefits in the area of therapeutics and drug discovery. This session will focus on all aspects related to emerging concept of ‘cells in chips’ that is driven by the need to use microfluidics to (1) control cellular environment with fine spatial and temporal resolution (2) parallelize and automate cell-based analysis (3) integrate sensitive detection methods for intracellular components and whole cells. In particular, research studies involving integrated microfluidic approaches to single-cell analysis for disease diagnostics are of special interest. These may incorporate live cell biochemical (metabolites, electrolytes, ions) or physical (morphology and mechanics) measurements. In this session, we invite papers describing microfluidic technology to probe chemical and biochemical responses at the cellular and sub-cellular levels. In addition, we welcome fundamental studies focused on any related aspects including simulation and modeling studies, materials modification to improve system performance, substrate biochemistry, cellular rheology and novel sample preparation protocols.
Primary SponsorTopical 3: 2007 Annual Meeting of the American Electrophoreses Society (AES) (T3)

Chair

Nimisha Srivastava
Postdoctoral Fellow
Biosystems Research Department
Sandia National Laboratories
Livermore, CA 94551
Phone Number: 925-294-2507
Fax Number: 925-294-3020
Email: nsrivas@sandia.gov

CoChair

Siva A. Vanapalli
Postdoctoral Fellow
Physics of Complex Fluids
University of Twente
Enschede, 7500 AE
Netherlands
Phone Number: 31 (0) 063 393 7777
Email: Siva.Vanapalli@tnw.utwente.nl
Single Molecule Lamda-DNA Stretching Studied by Microfluidics and Single Particle Tracking
Jun Wang, Agricultural and Biological Engineering, Purdue University, West Lafayette, IN 47907 and Chang Lu, Agriculture and Biological Engineering, Chemical Engineering, Purdue University, West Lafayette, IN 47906
Chemotaxis of E. Coli in a Microfluidic Device: Experiments and Simulations
Rajitha Vuppula, Chemical Engineering, IIT Bombay, Powai, Mumbai - 400 076, India, Mahesh S. Tirumkudulu, Department Of Chemical Engineering, IIT Bombay, Powai, Mumbai - 400 076, India and K. V. Venkatesh, Chemical Engineering, Indian Institute of Technology Bombay, Dept of Chemical Eng, IIT Bombay Powai, Mumbai, 400076, India
Microfluidic Devices For Local Rheological Characterization Of Viscoelastic Biological Materials
Danial N. Hohne, Chemical Engineering, University of Michigan, 3074 HH Dow, 2300 Hayward St., Ann Arbor, MI 48109, John G. Younger, Department of Emergency Medicine, University of Michigan, 4063 BSRB Box 2200, Ann Arbor, MI 48109 and Michael J. Solomon, Department of Chemical Engineering, University of Michigan, 2300 Hayward Street, Ann Arbor, MI 48109
Linear Amplification Of Mrna Using Microfluidic Systems For Gene Expression Analysis
Jason G. Kralj1, Audrey Player2, Ernest Kawasaki2 and Laurie E Locascio1, (1)Biochemical Sciences, National Institute of Standards and Technology, 100 Bureau Dr, MS 8313, Gaithersburg, MD 20899, (2)National Cancer Institute/National Institutes of Health, 8717 Grovemont Circle, Bethesda, MD 20877
Label-Free DNA Detection In Microchannels By A Reversible Light Diffracting Mesophase
Faisal Shaikh and Victor M. Ugaz, Artie McFerrin Department of Chemical Engineering, Texas A&M University, 3122 TAMU, College Station, TX 77843
Integrated Micro System For High Resolution Imaging And High-Throughput Sorting Of C. Elegans
Kwanghum Chung, Matthew Crane and Lu Hang, Gatech, 311 Ferst Dr. NW, Atlanta, GA 30332
Generation Of Microenvironments With Controlled Mechanical Properties For Analysis Of Mouse Embryonic Stem Cell Fate
Bong Geun Chung, Benjamin S. Gillers, Shamit Shrivastava and Ali Khademhosseini, Harvard-MIT, Division of Health Science and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139

Topical 3: 2007 Annual Meeting of the American Electrophoresis Society (AES)