Preliminary Program subject to change
TI020 Comminution - Experiments, Theory & Modeling
OverviewThis session solicits papers in all aspects of particle size reduction, breakage and/or fragmentation, either in milling, processing or as a result of transport. Both experimental and computational papers are welcomed, as well as modeling of all types including DEM and population balance approaches.
Primary SponsorTopical I: Pharmaceutical Engineering for the 21^st Century (TI)

Chair

R. Bertrum Diemer Jr.
Principal Division Consultant
DuPont Engineering Research & Technology
DuPont Company
1007 Market Street
Brandywine Building 8454
Wilmington, DE 19898
Phone Number: 302-774-2232
Email: r-bertrum.diemer@usa.dupont.com

CoChair

Ecevit Bilgili
Senior Research Chemical Engineer
Global Pharmaceutical Commercialization, Merck Manufacturing Division
Merck & Co., Inc.
WP 78-110, P.O. Box 4
West Point, PA 19486
Phone Number: 215-652-9824
Fax Number: 215-652-2821
Email: ecevit_bilgili@merck.com
Welcoming Remarks
Combination of Experimental and Mathematical Techniques for Characterization of Particle Friability
Pavol Rajniak1, Rong Fan2, Luke Schenck1, Kumar Dhanasekharan2 and Rey Chern1, (1)Merck & Co, Inc., WP78-110, PO Box 4, West Point, PA 19486, (2)Fluent Inc., 10 Cavendish Court, Lebanon, NH 03766
Analysis of Aspirin Milling in Single Ball Mill
R. Bertrum Diemer1, Yulong Ding2, Dolapo Olusanmi2, Mojtaba Ghadiri2, K. J. Roberts2 and Jon H. Olson3, (1)DuPont Engineering Research & Technology, DuPont Company, 1007 Market Street, Wilmington, DE 19898, (2)Institute of Particle Science & Engineering, University of Leeds, Clarendon Road, Leeds, LS2 9JT, United Kingdom, (3)Chemical Engineering, University of Delaware, Colburn Laboratory, Newark, DE 19716
Optimization of Milling Using Attainable Region Theory
Matthew J. Metzger1, Benjamin Glasser1, David Glasser2, Brendon Hausberger2, Diane Hildebrandt2 and Ngangezwe Khumalo2, (1)Chemical and Biochemical Engineering, Rutgers University, 98 Brett Rd, Piscataway, NJ 08854, (2)School of Chemical and Metallurgical Engineering, University of the Witwatersrand, Johannesburg, 1 Jan Smut Avenue, Johannesburg, South Africa
Numerical Simulation and Optimization of Grinding in Hammer Mill
Bodhisattwa Chaudhuri, Pharmaceutical Sciences, University of Connecticut, 69 N. Eagleville Road, Storrs, CT 06269
Break
The Breakage Matrix Approach in Evaluating Inadvertent Breakage of Dense Particulate Mixtures
A. Abu Nahar, Chemical and Process Engineering, University of Surrey, School of Engineering, Guildford, gu27xh, United Kingdom and U Tüzün, University of Surrey, School of Engineering, Guildford, gu27xh, United Kingdom
Effects of Co-Milling on Crystallinity of Salbutamol Sulphate Using Adipic Acid
Prashant N. Balani1, Wai Kiong Ng2, Sui Yung Chan1 and Reginald B.H. Tan2, (1)Department of Pharmacy, National University of Singapore, Science Drive 4, Singapore, 117543, Singapore, (2)Crystallisation and Particle Science, Institute of Chemical and Engineering Sciences, 1 Pesek Road, Jurong Island, Singapore, 627833, Singapore
Application of Box–Behnken Design and Response Surface Methodology for Modeling of Grinding Beach Sand Ore Using Ball Mill
Asha Immanuel Raju Chaduvula1, Murali Yugandhar Nikku2, Kiran Kumar Nalla2, Venkata Satya Chappidi2, Srinivasa babji Josyula2 and Israel Yedluri3, (1)Chemical Engineering, Andhra University, Andhra University, Visakhapatnam - 530 003, AP, INDIA, Visakhapatnam, 530003, India, (2)Chemical Engg Dept, Andhra University, Andhra University, Visakhapatnam - 530 003, AP, INDIA, Visakhapatnam, 530003, India, (3)Andhra University, Andhra University, Andhra University, Visakhapatnam - 530 003, AP, INDIA, Visakhapatnam, 530003, India

Topical I: Pharmaceutical Engineering for the 21Century