Preliminary Program subject to change
TA001 Genomic Approaches to Systems Biology
OverviewWith high-throughput genomic technology becoming so prevalent, the natural next question is how to make use of such information. The goal for this session is to discuss how and where genomic technology is being used to advance or complement our understanding of systems biology. Likewise, is systems biology informing our approach to genomics? Research describing the development and testing of new hypotheses, as well as describing new techniques relating genomics and systems biology are welcome.
Primary SponsorTopical A: Systems Biology (TA)

Chair

Peter J. Woolf
Assistant Professor
Chemical Engineering
University of Michigan
Ann Arbor, MI 48109-2136
Phone Number: 734-647-7985
Email: pwoolf@umich.edu

CoChair

Arul Jayaraman
Assistant Professor
Texas A&M University
Department of Chemical Engineering
3122 TAMU
College Station, TX 77840
Phone Number: 617-371-4874; 979-845-3361
Fax Number: 979-845-6446
Email: arul.jayaraman@chemail.tamu.edu
Deducing Hidden Transcription Networks And Regulatory Signals From Gene Expression Data
Mark P. Brynildsen1, Tung-Yun Wu2, Shi-Shang Jang2 and James C. Liao1, (1)Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, 5513 Boelter Hall, 420 Westwood Plaza, Los Angeles, CA 90095, (2)Department of Chemical Engineering, National Tsing-Hua University, Hsinchu, 30043, Taiwan
Single Chip Quality Assessment for Two-Color Microarrays
Patrick D. McMullen, Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60202, Luis A. N. Amaral, Chemical and Biological Engineering, Northwestern University, 2145 Sheridan Rd, TECH E136, Evanston, IL 60208 and Richard I. Morimoto, Biochemistry, Molecular Biology & Cell Biology, Northwestern University, IL
Comparison Of Multiple Stress Responses Of A Systematically Perturbed System
Bhaskar Dutta, University of Maryland, 2113 Chemical and Nuclear Engineering Building, College Park, MD 20742-2111, Harin H. Kanani, Chemical and Biomolecular Engineering, University of Maryland, College Park, 2113 Chemical and Nuclear Engineering Building, College Park, MD 20742-2111, John Quackenbush, Department of Biostatistics, Dana-Farber Cancer Institute, Mayer 232, 44 Binney Street, Boston, MA 02115 and Maria Klapa, Institute of Chemical Engineering and High-Temperature Chemical Processes, Foundation for Research and Technology-Hellas (FORTH), Stadiou St., Platani, Patras, Greece
Combining Computational And Experimental Methods To Identify Genes With Metabolic Functions
Jennifer L. Reed1, Trina R. Patel1, Keri H. Chen1, Andrew R. Joyce1, Margaret K. Applebee2, Christopher D. Herring1, Olivia T. Bui1, Eric M. Knight1, Stephen S. Fong3 and Bernhard O. Palsson4, (1)Bioengineering, University of California, San Diego, La Jolla, CA 92093-0412, (2)Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093-0412, (3)Department of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, VA 23284-3028, (4)University of California, San Diego, 9500 Gilman Dr. Dept. 0412, La Jolla, CA 92093-0412
Break
Utilizing Variation In Gene Expression To Quantify DNA Damage
Michael G. Benton1, Nathaniel R. Glasser2 and Sean P. Palecek2, (1)Cain Department of Chemical Engineering, Louisiana State University, South Stadium Drive, Rm 110, Baton Rouge, LA 70803, (2)Chemical and Biological Engineering, University of Wisconsin - Madison, 1415 Engineering Drive, Madison, WI 53706
Biological Pathway-Centric Approach to Integrative Analysis of Array Data as Applied to Mefloquine Neurotoxicity
Jerry W. Jenkins1, Jonathan E. Hood1, Abhishek S. Soni1, Shankar Sundaram1, Michael Aschner2 and Chih-Thai Jiang2, (1)Biomedical Technologies, CFD Research Corporation, 215 Wynn Drive, Suite 501, Huntsville, AL 35805, (2)Pediatrics and Pharmacology, Vanderbilt University Medical Center, 1162 Twentyfirst avenue, Nashville, TN 37232
Knowledge Driven Matrix Factorization To Reconstruct Modular Gene Regulatory Network
Zheng Li1, Shireesh Srivastava2, Yang Zhou3, Rong Jin3 and Christina Chan4, (1)Department of Chemical Engineering and Material Science, Michigan State University, 2527 Engineering Building, East Lansing, MI 48824, (2)Michigan State University, 2527 Engineering Building, East Lansing, MI 48824, (3)Computer Science and Engineering, Michigan State University, East Lansing, MI 48824, (4)Chemical Engineering and Material Science, Michigan State University, 2527 Engineering Building, East Lansing, MI 48824

Topical A: Systems Biology