Preliminary Program subject to change
TA003 Multiscale Systems Biology
OverviewA fundamental goal of systems biology is to integrate different component parts of a biological system to understand the workings of the whole. Oftentimes the whole biological system will span either multiple time or spatial scales, if not both. The goal of this session is to discuss research that allows us to better understand such multiscale systems. Papers on both experimental and computational studies are welcome.
Primary SponsorTopical A: Systems Biology (TA)

Chair

Jason Haugh
Associate Professor
Chemical & Biomolecular Engineering
North Carolina State University
Box 7905, Engineering Bldg. I
911 Partners Way
Raleigh, NC 27695-7905
Phone Number: (919) 513-3851
Fax Number: (919) 515-3465
Email: jason_haugh@ncsu.edu

CoChair

Anand R. Asthagiri
Chemical Engineering
California Institute of Technology
1200 E. California Blvd MC 210-41
Pasadena, CA 91125
Phone Number: 626-395-8130
Email: anand@cheme.caltech.edu
Molecular Systems Biology Via Multiscale Modeling And High-Performance Computing
Ravi Radhakrishnan1, Andrew Shih2, Jeremy Purvis2, Yingting Liu2 and Neeraj Agrawal2, (1)Department of Bioengineering, University of Pennsylvania, 120 Hayden Hall, 3320 Smithwalk, Philadelphia, PA 19104, (2)University of Pennsylvania, 120 Hayden Hall, 3320 Smithwalk, Philadelphia, PA 19104
Coarse-Grained Dynamics Of A Neural Field Model
Thomas A. Frewen1, Carlo R. Laing2 and Ioannis G. Kevrekidis1, (1)Department of Chemical Engineering, Princeton University, Engineering Quadrangle, Princeton, NJ 08544, (2)Institute of Information and Mathematical Sciences, Massey University, Private Bag 102-904 NSMC, Auckland, New Zealand
A Multiscale Systems Model For Platelet Signaling And Activation
Jeremy Purvis, Institute for Medicine and Engineering, University of Pennsylvania, 3340 Smith Walk, 1150 Vagelos Laboratories, Philadelphia, PA 19104 and Scott L. Diamond, Department of Chemical and Biomolecular Engineering, University of Pennsylvania, 3340 Smith Walk, 1150 Vagelos Labs, Philadelphia, PA 19104
Multiscale Stochastic Analysis Of The Gal Switch In Saccharomyces Cerevisiae: Modeling And Experiments
Vinay Prasad, Dept. of Chemical Engineering, University of Delaware, 150 Academy Street, Newark, DE 19716 and K. V. Venkatesh, Chemical Engineering, Indian Institute of Technology Bombay, Dept of Chemical Eng, IIT Bombay Powai, Mumbai, 400076, India
Rasgrp-Dependent Feedback Regulation Of Sos Contributes To Digital Erk Responses And Efficient Lymphocyte Activation
Jayajit Das, Chemical Engineering, Massachusetts Institute of Technology, E19-238, 70 Massachusetts Avenue, Cambridge, MA 02139, Jeroen Roose, Department of Anatomy, School of Medicine, University of San Francisco at California, SanFrancisco, 94143, Arthur Weiss, Department of Medicine, The Rosalind Russell Medical Research Center for Arthritis and Howard Hughes Medical Institute, University of San Francisco at California, 94143 and Arup K. Chakraborty, Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139
Single-Cell Math Model With Experimental And Math Analysis Of The Apoptosis Regulatory Network
John M. Burke1, John G. Albeck2, Peter K. Sorger2 and Douglas A. Lauffenburger3, (1)Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 56-291, Cambridge, MA 02139, (2)Systems Biology, Harvard Medical School, 200 Longwood Ave, WAB 438, Boston, MA 02115, (3)Biological Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, 56-341, Cambridge, MA 02139

Topical A: Systems Biology