Tuesday, November 6, 2007 - 2:10 PM
246e

3D Self-Assembled Microdevices for Cell Therapy and Chemical Delivery

Timothy Leong1, Christina Randall2, Noy Bassik1, and David H. Gracias1. (1) Department of Chemical and Biomolecular Engineering, Johns Hopkins University, 125 Maryland Hall, 3400 N Charles Street, Baltimore, MD 21218, (2) Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218

We describe a new class of biomedical microdevices based on self-assembling 3D polyhedra. The polyhedra are fabricated from lithographically structured 2D templates and fold on a thermal trigger. We have utilized the polyhedra as containers for on-demand remote controlled delivery to live cells and in tissue. We will also describe experiments in cell encapsulation and imaging.


Web Page: www.jhu.edu/chbe/gracias/