A two dimensional model for a mesh contactor utilised for acetone stripping from binary mixtures acetone-isopropanol with nitrogen as inert gas, as well as for asymmetric transfer hydrogenation of acetophenone with isopropanol as hydrogen donor in the presence of a homogeneous catalyst has been formulated and solved. The microstructured mesh contactor consists of parallel metal plates, gaskets and a microstrucutured mesh so that passages for gas and liquid phases are formed. Each plate has width x length of 3 x 8 cm, whilst the gasket thickness which determines the thickness of gas and liquid film on each side of the mesh is 0.2 mm. The mesh is made of stainless steel 304, has a thickness of 0.05 mm, an average pore size of 0.075 mm and a regular pore arrangement corresponding to 23 % open area. The model gives good agreement with experimental data for both acetone removal from a binary mixture and asymmetric transfer hydrogenation. Theoretical and experimental investigations show that the amount of acetone removed from the liquid phase is strongly dependent on the ratio of inlet gas and liquid flowrate. For higher ratio, more efficient acetone removal from the liquid phase is achieved. Regardless of inlet acetone concentration, the average acetone concentration in the cross section related to the inlet concentration, along the reactor is the same at constant reactor geometry and inlet ratio. If dry nitrogen is used as stripping agent, simultaneous evaporation of acetone and isopropanol results in significant solvent depletion of the liquid phase. In this case the gas phase becomes saturated with solvent (isopropanol) near the reactor entrance. In order to avoid solvent evaporation which can lead to unwanted concentration of the liquid phase and solvent loss, the gas phase can be saturated with isopropanol before entering the reactor. The reactor model was further used to investigate asymmetric transfer hydrogenation of acetophenone. Due to efficient removal of acetone produced as by-product during the reaction, high conversion (>99 %) can be achieved for residence time of about 10 min, which is much shorter than the time necessary to achieve similar conversion in a laboratory batch reactor.