Biological macro/supramolecules such as DNA, proteins and viruses hold great promise as templates for nanodevice fabrication due to the inherent advantages over inorganic materials such as selectivity, mild processing conditions and precise self-assembly mechanisms nature has provided. Despite recent advances in discovering novel properties of various nanoscale entities, reliable fabrication of nanodevices remains challenging due to the lack of facile assembly techniques that allow high spatial and orientational control. To address this we have developed biochemically driven patterned assembly of potent viral nanotemplates onto inorganic substrates. Specifically, Tobacco Mosaic Viruses serve as high capacity nanotemplates via a genetically inserted cysteine on each coat protein, which provides covalent coupling sites. These functionalized nanotemplates were partially stripped and assembled onto capture DNA surfaces through hybridization with its own genomic RNA. Fluorescence and SEM images show high spatial, orientational and sequence specificity as well as stability of the patterned TMV templates . Further, simultaneous assembly of multiple TMVs onto printed DNA microarray platforms at readily addressable locations via linker DNA hybridization based programming is demonstrated. Our recent progress on hierarchical assembly of these potent nanoentities will also be presented.