Converting biological discoveries into commercial-scale processes requires that graduating chemical engineers obtain an understanding of modern bioprocess principles. This paper describes the development and implementation of a five week long protein production project into a multidisciplinary upper level elective course on bioprocess engineering.

The protein production project was developed and implemented during the fall 2006 semester. A key element of the protein production project was the competition between student groups. Group performance was rated using a production rubric, and the team with the highest score was guaranteed an “A” on the project. The rubric included equipment rental costs and production bonuses for producing large quantities of protein of high purity. The equipment rental costs were carefully determined to encourage continued student experimentation in the laboratory. The protein production project was mentioned as the “best feature of the course” on over half of the student course evaluations.