Complex 3D Scaffolds for Cell Culture

Tuesday, November 18, 2008: 4:39 PM
Salon L (Marriott Philadelphia Downtown)

Noy Bassik, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD
George Stern, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD
Mustapha Jamal, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD
David H. Gracias, Department of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, MD

Tissues often have complex toplogies, but it is still challenging to construct microstructured scaffolds for culturing cells in non-planar 3D geometries. We describe a strategy to self-assemble complex micropatterned structures such as coils, spirals and cylinders. We investigated the use of these substrates as scaffolds for cell culture in 3D.
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