Science and Engineering in Crystallization

Friday, November 21, 2008: 8:00 AM
Room 107-B (Pennsylvania Convention Center)

Description:
Robust crystallization of API with desired properties often requires a seamless interface between crystallization science and engineering principles. Crystallization science governs the chemical interactions that drive both nucleation and growth. Engineering principles provide the tools for scale-up and finesse the process. In this section, we invite authors to submit papers that apply both science and engineering to solve challenging scale-up problems, such as polymorph and enantiomer crystallization, particle size manipulation, and habit modification, to name a few.


Sponsor:
Pharmaceuticals
Co-Sponsor(s):
Crystallization and Evaporation (02b)


Chair:
Hector Guzman
Email: hguzman@tpius.jnj.com

CoChair:
Monica H. Lamm
Email: mhlamm@iastate.edu


8:00 AM
(744a) Linear Models for Prediction of Ibuprofen Crystal Morphology Based on Hydrogen Bonding Propensities
Charles Acquah, Arunprakash T. Karunanithi, Matthew Cagnetta, Luke E. K. Achenie and Steven Suib

8:40 AM
(744c) Polymorph Selection In Solution Crystallization: Is Kinetics the Primary Determinant?
Sendhil K. Poornachary, Guangjun Han, Pui Shan Chow and Reginald B. H Tan

9:20 AM
(744e) Precise Tailoring of the Crystal Size Distribution by Optimal Seeding Time Profiles
Nicholas Kee, Xing Yi Woo, Reginald B. H Tan and Richard D. Braatz

9:40 AM
(744f) Development and Scale-up of a Seeded Acidic Co-Addition Crystallization
Adam S. Butterbaugh, Kevin D. Seibert and Paul C. Collins

10:00 AM
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division