Protein Engineering I: Therapeutics

Tuesday, November 18, 2008: 8:30 AM
Room 107-B (Pennsylvania Convention Center)

Description:
The ability to create proteins with desired properties is limited by our current understanding of the relationships between protein sequence, protein structure and protein function and by our current abilities to search sequence space in an efficient manner. This session seeks presentations on emerging topics and recent successes in both the understanding and engineering of protein form and function. Experimental and computational approaches that are of scientific, medical, and industrial significance are sought after. Possible areas of interest include, but are not limited to: computational design, directed evolution, protein mutations and modifications including non-natural amino acids, antibody or cytokine engineering, and protein medicinal chemistry.


Sponsor:
Bioengineering


Chair:
George Georgiou
Email: gg@che.utexas.edu

CoChair:
Scott Banta
Email: sbanta@cheme.columbia.edu


8:30 AM
(242a) Affinity Maturation of Antibody Fragments Containing Non-Canonical Amino Acids
James A. Van Deventer, Tae Hyeon Yoo and David A. Tirrell

9:30 AM
(242d) Developing Therapeutic Proteins by Engineering Ligand-Receptor Interactions
Douglas S. Jones, Stayce E. Beck, Stephen S. Lee and Jennifer R. Cochran

9:50 AM

10:00 AM
(242e) Novel Enzyme-Prodrug Therapy for Cancer
Roger G. Harrison, Yahya A. Lazrak, Luis F.F. Neves, Peter S. McFetridge and Arafat Tfayli

10:20 AM
(242f) Fabrication of Engineered Collagen-Like Biopolymers
Sam Wei Polly Chan, She-pin Hung, Richard Lathrop, Nancy A. Da Silva and Szu-Wen Wang
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division