Session: Multiscale Systems Biology (2008 Annual Meeting)

Monday, November 17, 2008: 12:30 PM

Washington C Room (Loews Philadelphia Hotel)

Description:

A fundamental goal of systems biology is to integrate different component parts of a biological system to understand the workings of the whole. Oftentimes the whole biological system will span either multiple time or spatial scales, if not both. The goal of this session is to discuss research that allows us to better understand such multiscale systems. Papers on both experimental and computational studies are welcome.

Sponsor:

Topical A: Systems Biology

Chair:

Ravi Radhakrishnan
Email: rradhak@seas.upenn.edu

CoChair:

Yiannis Kaznessis
Email: yiannis@cems.umn.edu

12:30 PM

(101a) Predicting the Evolutionary Landscape of Multicellular Phenotypes
Anand R. Asthagiri

12:50 PM

(101b) Multiscale Stochastic Dynamical Models Calibrated from AFM Single-Molecule Time Series and Computer Simulations
Christopher P. Calderon, Ching-Hwa Kiang, Dennis D. Cox, Nolan C. Harris, Wei-Hung Chen and Kuan-Jiuh Lin

1:10 PM

(101c) Ligand Specificity of C-Fos Expression Emerges from Spatiotemporal Control of Erbb Network Dynamics
Takashi Nakakuki, Marc R. Birtwistle, Yuko Saeki, Noriko Yumoto, Nagashima Takeshi, Babatunde A. Ogunnaike, Hatakeyama Mariko and Boris N. Kholodenko

1:30 PM

(101d) Synthesis of Metabolic Pathways Using Thermodynamic Constraints and Parametric Sensitivity Analysis
Frank P. Marealle, Ye Wang, Jorge E. Gatica and María Rosa Hernández

1:50 PM

Break

2:00 PM

(101e) Host and Viral Factors Control Stochastic Behavior In HIV-1 Gene Regulation and Latency
Kathryn Miller-Jensen, Ron Skupsky, John C. Burnett, Adam P. Arkin and David V. Schaffer

2:20 PM

(101f) Stochastic Spatial and Non-Spatial Simulations of the Erbb Signaling Pathways Demonstrate the Importance of Spatial Organization In Signal Transduction
Michelle N. Costa, Dion Vlachos and Jeremy S. Edwards

2:40 PM

(101g) Reverse Engineering the Human Platelet
Jeremy E. Purvis, Manash S. Chatterjee, Lawrence F. Brass and Scott L. Diamond

See more of this Group/Topical: Topical A: Systems Biology

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