Session: Crystallization of Pharmaceutical and Biological Molecules I (2009 Annual Meeting)

Description:

This session welcomes papers addressing fundamental as well as applied studies in the area of crystallization of pharmaceutical or biological molecules. Topics related to experimental studies, theory and simulation that contribute to fundamental understanding of crystallization as well as industrial case studies on the crystallization development of pharmaceutical and biological compounds are encouraged.

Sponsor:

Crystallization and Evaporation

Co-Sponsor(s):

Pharmaceuticals (15b)

Chair:

Xing Wang
Principal Scientist
Novartis Pharmaceuticals Corporation
USEH, 436-4221, One Health Plaza
East Hanover, NJ 07936-1080
Phone Number: 862-778-9457
Email: xing2.wang@novartis.com

Co-Chair:

Daniel Jarmer

Papers:

252a

Nucleation of Molecular Crystals: Order Parameters and Minimum Free Energy Paths
Erik E. Santiso, Massachusetts Institute of Technology; Bernhardt L. Trout, Massachusetts Institute of Technology

252b

Strategies and Challenges for Making a Metastable Polymorph of a Pharmaceutical API
Bing Shi, Wyeth Pharmaceuticals; Richard Varsolona, Wyeth Pharmaceuticals; Jeremy Eberhardt, Wyeth Pharmaceuticals; Subodh Deshmukh, Wyeth Pharmaceuticals

252c

Design of LLPS Based Spherulitic Crystallization to Address Tableting Challenges
Venkateswarlu Bhamidi, Abbott Laboratories; Ahmad Sheikh, Abbott Laboratories; Todd McDermott, Abbott Laboratories; Larry Bartelt, Abbott Laboratories; Shailendra Bordawekar, Abbott Laboratories

252d

Chiral Separation Using a Novel Combination of Cooling Crystallization and a Hollow-Fiber Membrane Barrier
Apichit Svang-Ariyaskul, Georgia Institute of Technology; William J. Koros, Georgia Institute of Technology; Ronald W. Rousseau, Georgia Institute of Technology

252e

Optimization of a Distillative Crystallization for An API Intermediate
Nathan Domagalski, Bristol-Myers Squibb Company; Michaël Fenster, Bristol-Myers Squibb Company; Wendel Doubleday, Bristol-Myers Squibb Company; Jean Tom, Bristol-Myers Squibb Company

252f

A New Model for Capturing the Effect of Supersaturation On Crystal Shape
Michael A. Lovette, University of California at Santa Barbara; Michael F. Doherty, University of California at Santa Barbara

See more of this Group/Topical: Separations Division

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