This preliminary program is subject to change.

Reaction Engineering in Pharmaceuticals and Fine Chemicals


Description:
Presentations are solicited for reaction engineering in the development and scale-up of pharmaceutical and fine chemical processes. This work may include the integration of process analytical technology, modeling, and reactor design. Applications involving multiphase systems, mass transfer limited operations and novel reactor design on observed kinetic behavior is of particular interest to this session. Case studies that provide a better understanding of kinetics gained through process development are also encouraged to be submitted.

Sponsor:
Pharmaceuticals
Co-Sponsor(s):
Catalysis and Reaction Engineering Division (20)


Chair:
Johannes G. Khinast
Graz University of Technology
Institute for Process and Particle Engineering
Inffeldgasse 21/A
Graz A-8010
Phone Number: 0043 316 873 7978
Fax Number: 0043 316 873 7963
Email: khinast@tugraz.at

Co-Chair:
Justin M. Notestein

Papers:
Design of Continuous Processes for the Synthesis of Pharmaceutical Ingredients
Heidrun Gruber-Woelfler, Graz University of Technology; Peter Feenstra, Graz University of Technology; Paul Radaschitz, Graz University of Technology; Alexander Muhr, Graz University of Technology; Christoph Kutschera, Graz University of Technology; Johannes G. Khinast, Graz University of Technology
API Impurity Control - Utilizing Kinetic Modeling to Understand a Dynamic Reaction System
Sabrina Ivy, Bristol-Myers Squibb Company; Scott Jones, Bristol-Myers Squibb Company; Scott Savage, Bristol-Myers Squibb Company; Patrick Benitez, Bristol-Myers Squibb Company
On the Kinetics Investigation and Process Optimization of An API Intermediate
Nandkishor K. Nere, Abbott Laboratories; David R. Hill, Abbott Laboratories; Anthony Haight, Abbott Laboratories; James C. Marek, Abbott Laboratories; Michael G. Fickes, Abbott Laboratories; Shailendra V. Bordawekar, Abbott Laboratories
Automated Microfluidic System for Online Optimization of a Chemical Reaction Network
Jonathan P. McMullen, Massachusetts Institute of Technology; Klavs F. Jensen, Massachusetts Institute of Technology
Reaction Kinetic Modeling in the Development of Human Growth Hormone PEGylation Process
Sa .V Ho, Pfizer Global R&D; John J. Buckley, Pfizer Global R&D; Gopinath V. Annathur, Pfizer Global R&D; Kristin E Thomas, Pfizer Global R&D; Brandi Osborne, Pfizer Global R&D
Deactivation of TEM-1 Beta-Lactamase Investigated by Isothermal Batch and Non-Isothermal Continuous Enzyme Membrane Reactor Methods
Thomas A. Rogers, Georgia Institute of Technology; Roy M. Daniel, University of Waikato; Andreas S. Bommarius, Georgia Institute of Technology
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division