Session: Receptor-Mediated Phenomena (2009 Annual Meeting)

Description:

Cells sense and respond to their environment via receptor-mediated phenomena. In this session, we encourage talks that highlight spatial and dynamic aspects of receptor events, including the interplay between receptor trafficking and intracellular signaling, the coupling of mechanical stresses with cell signaling, receptor regulation, receptor-mediated therapeutic strategies, and cross-talk among receptor signaling pathways. Examples that integrate experiments with theory are particularly welcome.

Sponsor:

Engineering Fundamentals in Life Science

Chair:

David Klinke
Assistant Professor
West Virginia University
Department of Chemical Engineering
Morgantown, WV 26506-6102
Phone Number: 304-293-2111 ext 2432
Fax Number: 304-293-4139
Email: david.klinke@mail.wvu.edu

Co-Chair:

Kaushal Rege

Papers:

535a

Receptor-Mediated Transport of Nanoparticles for the Oral Delivery of Therapeutic Proteins
Erik C. Brewer, Drexel University; Anthony M. Lowman, Drexel University

535b

Detection of Single Molecule H2O2 Signaling From Epidermal Growth Factor Receptor (EGFR) On A431 Cells Using Fluorescent Single Walled Carbon Nanotubes
Hong Jin, MIT; Daniel A. Heller, Massachusetts Institute of Technology; Jingqing Zhang, MIT; Jong-Ho Kim, MIT; Michael S. Strano, Massachusetts Institute of Technology

535c

Novel Bispecific Fibronectin Domain Constructs Downregulate EGFR
Benjamin J. Hackel, Massachusetts Institute of Technology; K. Dane Wittrup, Massachusetts Institute of Technology

535d

Kinetic Model of EGF Receptor Activation and Inhibition
Calixte S. Monast, University of Pennsylvania; Matthew J. Lazzara, University of Pennsylvania

Break

535e

Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Phosphorylation Sustained by Immobilized VEGF
Sean M. Anderson, University of California, Los Angeles; Tom T. Chen, University of California, Los Angeles; Maha Rahim, University of California, Los Angeles; M. Luisa Iruela-Arispe, University of California, Los Angeles; Tatiana Segura, University of California, Los Angeles

535f

Effect of Ligand Spacing On Cell Adhesion and Rolling Under Flow
Travis Spain, University of Oklahoma; Aurore B. Van De Walle, University of Oklahoma; David W. Schmidtke, University of Oklahoma

535g

Reprogramming Innate Immune Cells to Probe and Modulate Immunosuppressive Tumor Microenvironments
Joshua N. Leonard, Northwestern University

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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