Session: Mathematical Approaches in Systems Biology I: Genome Scale Models (2009 Annual Meeting)

Description:

This session is devoted to theoretical and computational studies of biological systems. Such systems include protein/DNA interactions, protein/protein interactions, genetic networks, metabolic pathways, and signal transduction pathways. Presentations will focus on theoretical and computational developments for the study of the behavior of these systems in response to stimulation or changes in their kinetic and thermodynamic properties. Contributions of novel computational strategies for systems biology are especially welcome.

Sponsor:

Engineering Fundamentals in Life Science

Chair:

Rajanikanth Vadigepalli
Assistant Professor
Thomas Jefferson University
Daniel Baugh Institute for Functional Genomics and Computational Biology
1020 Locust St Room 381
Philadelphia, PA 19107
Phone Number: 215-955-0576
Fax Number: 215-503-2636
Email: raj@mail.dbi.tju.edu

Co-chairs:

Maciek R. Antoniewicz and Christopher Henry

Papers:

210a

Towards a Minimal Cell Model
Michael Shuler, Cornell University; Jordan Atlas, Cornell University

210b

Towards a Whole-Cell Model of Mycoplasma Genitalium
Markus W. Covert, Stanford University; Jayodita Sanghvi, Stanford University; Jonathan R. Karr, Stanford University

210c

Evolutionary Algorithms in Metabolic Flux Analysis: The Case for Optimizing Bio-Butanol Production in Clostridium Acetobutylicum
Ryan S. Senger, Virginia Polytechnic Institute and State University

210d

Optimization-Based Approach for Transcriptional Regulatory Network Refinement
Dipak Barua, University of Wisconsin-Madison; Joonhoon Kim, University of Wisconsin-Madison; Jennifer L. Reed, University of Wisconsin-Madison

Break

210e

In Silico and Experimental Studies of Cofactor Balance in the Engineered Pentose Sugar Utilization Pathways in Saccharomyces Cerevisiae
Amit Ghosh, University of Illinois Urbana Champaign; Jing Du, University of Illinois Urbana Champaign; Byoungjin Kim, University of Illinois Urbana Champaign; Ryan P. Sullivan, University of Illinois Urbana Champaign; Huimin Zhao, University of Illinois Urbana Champaign; Nathan D. Price, University of Illinois Urbana Champaign

210f

Improving Regulatory Information for the Yeast Metabolic Model iMM904 Using Synthetic Lethality Data
Alireza Zomorrodi, The Pennsylvania State University; Patrick F. Suthers, The Pennsylvania State University; Costas D. Maranas, The Pennsylvania State University

210g

Developing Metabolic Workhorses through in Silico Evolutionary Optimization: Case Studies in Flavonoid Biosynthesis
Zachary L. Fowler, University at Buffalo, the State University of New York; Joseph A. Chemler, University at Buffalo, the State University of New York; Kyle P. McHugh, University at Buffalo, the State University of New York; Mattheos A.G. Koffas, University at Buffalo, the State University of New York

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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