Session: Thermodynamics of Protein Folding and Aggregation (2009 Annual Meeting)

Description:

This session seeks submissions focused on experimental and theoretical characterization and prediction of the thermodynamics and mechanism(s) of protein folding, and the role of aggregation as an on- or off-pathway aspect of (un)folding. Aggregation in this context is intended to include both reversible association and net irreversible aggregate formation. Preference will be given to presentations that provide insights of general utility, and those focused on relatively complex (un)folding pathways such as multi-domain and natively multimeric proteins.

Sponsor:

Bioengineering

Chair:

Eva Chi
Assistant Professor
University of New Mexico
Department of Chemical and Nuclear Engineering
Albuquerque, NM 87131
Phone Number: 505-277-5431
Email: evachi@unm.edu

Co-Chair:

Inchan Kwon

Papers:

230a

Role of Structure and Stability of β-Amyloid Oligomers and Fibrils On Intracellular Pathways Associated with Alzheimer's Disease
Sudheer K. Sami, University of Maryland Baltimore County; Theresa A. Good, University of Maryland Baltimore County

230b

Lipid-Membrane Mediated Tau Misfolding and Aggregation
Philip Camp, University of New Mexico; Jacek Biernat, Max Planck Unit for Structural Biology; Eckhard Mandelkow, Max Planck Unit for Structural Biology; Jaroslaw Majewski, Los Alamos National Laboratory; Eva Chi, University of New Mexico

230c

Examining Polyglutamine Peptide Length: A Connection Between Collapsed Conformations and Increased Aggregation
Robert H. Walters, University of Wisconsin-Madison; Regina M Murphy, University of Wisconsin-Madison

230d

Quartz Crystal Microbalance Analysis of Amyloid-Beta Protein Assembly at a Biological Interface
Joseph A. Kotarek, University of South Carolina; Melissa Moss, University of South Carolina

Break

230e

Mutation Effects On Protein Folding Over Small Barriers
Troy Cellmer, National Institutes of Health; William Eaton, NIH/NIDDK

230f

Predictive Tools for Protein Aggregation
Naresh Chennamsetty, Massachusetts Institute of Technology; Vladimir Voynov, Massachusetts Institute of Technology; Veysel Kayser, Massachusetts Institute of Technology; Bernhard Helk, Novartis Pharma AG; Bernhardt L. Trout, Massachusetts Institute of Technology

230g

Complex Dynamics of Integrin Inserted Domain Unfolding Studied by Optical Tweezer
Cheng-Zhong Zhang, Harvard Medical School; Joonil Seog, Univeresity of Maryland; Jesse Dill, University of Berkeley; Steve B. Smith, University of Berkeley; Frank X. Zhang, Department of Pathology, Harvard medical school; Ciro Cecconi, University of Berkeley; Susan Marqusee, University of Berkeley; Carlos Bustamante, University of Berkeley; Timothy A. Springer, Department of Pathology, Harvard medical school

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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