This preliminary program is subject to change.

Protein Engineering I - Therapeutics


Description:
This session will focus on protein engineering for therapeutic applications with an emphasis on emerging topics and recent successes. Possible areas of interest include, but are not limited to, (1) advances in protein-based therapeutics, (2) proteins for cellular targeting and imaging, (3) proteins involved in disease pathology, and (4) protein-based biomaterials.

Sponsor:
Bioengineering


Chair:
Scott Banta
Columbia University
Department of Chemical Engineering
New York, NY 10027
Phone Number: 212-854-7531
Fax Number: 212-854-3054
Email: sb2373@columbia.edu

Co-Chair:
Szu-Wen Wang

Papers:
Tumor Idiotype-Based Virus-Like Particle Vaccines for B-Cell Lymphoma
Kedar G. Patel, Stanford University; Patrick P. Ng, Stanford University; Shoshana Levy, Stanford University; Ronald Levy, Stanford University; James R. Swartz, Stanford University
Tumor Targeting Fibronectin Domains
Benjamin J. Hackel, Massachusetts Institute of Technology; K. Dane Wittrup, Massachusetts Institute of Technology
Towards the Rational Design of p53 Stabilizing Drugs: Probing the Surface of the Oncogenic Y220C Mutant
Joel L. Kaar, Medical Research Council Centre for Protein Engineering; Nicolas Basse, Medical Research Council Centre for Protein Engineering; Giovanni Settanni, Medical Research Council Centre for Protein Engineering; Andreas C. Joerger, Medical Research Council Centre for Protein Engineering; Trevor J. Rutherford, Medical Research Council Centre for Protein Engineering; Alan R. Fersht, Medical Research Council Centre for Protein Engineering
Targeting the Vasculature of Solid Tumors with Enzyme/Prodrug and Methionine-Depletion Therapy
Yahya A. Lazrak, University of Oklahoma; Brent D. Van Rite, University of Oklahoma; Magali Pagnon, University of Oklahoma; Arafat Tfayli, University of Oklahoma Health Sciences Center; Peter S. McFetridge, University of Oklahoma; Roger G. Harrison, University of Oklahoma
Direct Epitope Mapping of T Cells From Influenza A Virus Genome Using Yeasts Displaying MHC-Peptide Complexes as Artificial Antigen Presenting Cells
Fei Wen, University of Illinois at Urbana-Champaign; Olga Esteban, University of Illinois; Huimin Zhao, University of Illinois at Urbana-Champaign
Design of a Peptide Probe for Rapid and Specific Detection of Amyloid Oligomers
Yang Hu, Polytechnic Institute of New York University; Chung-sei Kim, Polytechnic Institute of New York University; Michael Hernandez, Polytechnic Institute of New York University; Jorge Ghiso, New York University Langone Medical Center; Agueda A. Rostagno, New York University Langone Medical Center; Jin Ryoun Kim, Polytechnic Institute of New York University
Directed Evolution and Structural Characterization of A Simvastatin Synthase
Xinkai Xie, University of California at Los Angeles; Xue Gao, University of California at Los Angeles; Inna Pashkov, University of California at Los Angeles; Micheal Sawaya, University of California at Los Angeles; Jenal Laidman, University of California at Los Angeles; Wenjun Zhang, University of California at Los Angeles; Ralph Cacho, University of California at Los Angeles; Todd Yeates, University of California at Los Angeles; Yi Tang, University of California at Los Angeles
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division