Session: Downstream Processing: Harvest/Recovery (2009 Annual Meeting)

Description:

This session will focus on highlighting the latest advances in downstream processing relevant to harvest/recovery operations including rapid process development, improved efficiency, cost reduction, integration of operations and handling of high titre streams. Topics to be covered include, but are not limited to: Centrifugation, filtration, adsorption, extraction, precipitation and expanded bed chromatography.

Sponsor:

Bioengineering

Co-Sponsor(s):

Pharmaceuticals (15b)

Chair:

Sanjeev Katti
Director Chemical Process Development
Genzyme
153 Second Avenue
Waltham, MA 02451
Phone Number: 781-434-3496
Email: sanjeev.katti@genzyme.com

Co-Chair:

Nihal Tugcu

Papers:

511a

Coupling Clarification and Purification Into a Single Unit Operation for Improved High-Titer Mammalian-Based Processing
Joshua Walker, Biogen Idec; Jon Romero, Biogen Idec

511b

Process Improvement of Tangential Flow Filtration Harvest of a Monoclonal Antibody From NS0 Cell Culture: A Case Study
Ying Zhu, Facet Biotech, Inc.; Amit Varma, Facet Biotech, Inc.

511c

Evaluation of a Centrifugation Scale-Down System for Bench-Scale Process Development
Matthew Westoby, Biogen Idec; Yik Lam, Biogen Idec; Ryan Haverstock, Biogen Idec; Carson Fuller, Biogen Idec; Katie Golson, Biogen Idec

511d

Modeling Buffer Preparation Operations for Downstream Processing
Charles Siletti, INTELLIGEN, INC.; Demetri Petrides, INTELLIGEN, INC.

Break

511e

Viscosity Reduction through Co-Expression of Nuclease for Improved Clarification
Bangaru Balasundaram, University College London; Darren Nesbeth, University College London; John Ward, University College London; Eli Keshavarz-Moore, University College London; Daniel Bracewell, University College London

511f

Characterization of Rabies Virus Vaccine Inactivation
Veysel Kayser, Massachusetts Institute of Technology; Bernhardt L. Trout, Massachusetts Institute of Technology

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

<< Previous Session | Next Session >>