Session: Building Drug and Gene Delivery Into Tissue Engineering (2010 Annual Meeting)

Description:

This session will focus on the development of new materials or methods for the controlled delivery of macromolecular therapeutics (proteins, DNA and siRNA) from cellular scaffolds. Appropriate topics would include new chemistries/methods for degradation-controlled release, layer-by-layer fabrication and release, cell-mediated therapeutic release, and other triggered release technologies. Further, the use of such technologies to achieve in vivo and ex vivo regenerative therapies or in vitro cell manipulation for other applications is also appropriate.

Sponsor:

Biomaterials

Chair:

Tatiana Segura
University of California, Los Angeles
Chemical and Biomolecular Engineering
420 Westwood Blvd.
Los Angeles, CA 90095
Email: tsegura@ucla.edu

Co-Chair:

Danielle Benoit
Assistant Professor
University of Rochester
Department of Biomedical Engineering
Robert B. Goergen Hall
Rochester, NY 14627
Phone Number: 585-275-4620
Email: benoit@bme.rochester.edu

Papers:

85a

DNA-Containing Polyelectrolyte Multilayers: Fluorescently Labeled Polymers Shed Light On the Roles That Cationic Polymers Play in Promoting Surface-Mediated Cell Transfection
Shane L. Bechler, University of Wisconsin - Madison; Christopher M. Jewell, University of Wisconsin - Madison; Ryan M. Flessner, University of Wisconsin - Madison; David M. Lynn, University of Wisconsin - Madison

85b

Properties of the Cell-Biomaterial Interface That Influence Nonviral Gene Delivery
Beth A. Duensing, University of Nebraska-Lincoln; Tadas Kasputis, University of Nebraska-Lincoln; Angela K. Pannier, University of Nebraska-Lincoln

85c

Tunability of Cell-Triggered DNA Release From a Substrate-Mediated Delivery System
Kory M. Blocker, University of Delaware; Kristi L. Kiick, University of Delaware; Millicent O. Sullivan, University of Delaware

85d

Lentiviral Gene Delivery From Hydrogel Filled PLG Scaffolds
Misael O. Aviles, Northwestern University; Lonnie D. Shea, Northwestern University

85e

Sustained and Localized Delivery Systems with Virus-Polymer Hybrid
Kye Il Joo, University of Southern California; Yuning Lei, University of Southern California; Biliang Hu, University of Southern California; Pin Wang, University of Southern California

85f

Microspotting of Adeno-Associated Virus for Combinatorial Genetic Testing
Kellie I. McConnell, Rice University; Ryan Schweller, Rice University; Michael Diehl, Rice University; Junghae Suh, Rice University

See more of this Group/Topical: Materials Engineering and Sciences Division

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