This preliminary program is subject to change.

Advances in Cell Culture I: Experimental


Description:
Overview: This session intends to cover the state-of-the-art in mammalian, plant, algal and insect cell culture toward the production of biofuels, pharmaceuticals, vaccines and high-value secondary metabolites. Topics for this session focus on experimental methods which include, but are not limited to, cell line development and engineering, genomics, metabolomics and proteomics analysis, high throughput cell culture screening systems, media development, bioreactor design and operation scale-up and scale-down methodologies, improvement of yield recombinant protein or vaccines yield through process optimization, process characterization and control.

Sponsor:
Bioengineering


Chair:
Christie A.M. Peebles
Assistant Professor
Colorodo State University
Chemical Engineering
Fort Collins, CO 80523
Phone Number: 970-491-5252
Email: christie.peebles@colostate.edu

Co-Chair:
Weiwei Hu
Senior Engineer
Biogen Idec
BioPharm Development
5200 Research Place
San Diego, CA 92122
Phone Number: ?
Email: weiwei.hu@biogenidec.com


Papers:
74a
Cell Cycle Arrest Engineering to Enhance Production Phase in CHO Cell Culture
Matthew P. Zustiak, Johns Hopkins University; Yueqing Xie, Biopharmaceutical Development Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick; Jianwei Zhu, Biopharmaceutical Development Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick; Michael J. Betenbaugh, Johns Hopkins University
74b
Development of a Constitutive Promoter Library for Optimization of Cell Lines
Joshua Ferreira, Stanford University; Ryan Peacock, Stanford University; Ingrid Lawhorn, Stanford University; Clifford Wang, Stanford University
74c
Optimizing High Dimensional CHO Cell Culture Processes with Multiple Responses in Chemically-Defined Media Using a Nonlinear Experimental Design Method
Guiying Laurel Zhang, Amgen; Jonathan Lull, Amgen; Matthew Jerums, Amgen; Shun Luo, Amgen; Thomas Seewoester, Amgen
74d
Investigation of Stress Protein Expression and Hydrodynamic Conditions in Various Cell Cultures Vessels
Claudia Berdugo, The Ohio State University; Jeffrey J. Chalmers, The Ohio State University
74f
High-Throughput Quantification of Glycoprotein Sialylation
Lam Raga Anggara Markely, Massachusetts Institute of Technology; Daniel I. C. Wang, Massachusetts Institute of Technology
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division