This preliminary program is subject to change.

Advances in Cell Culture II : Metabolic Flux Analysis and Modeling


Description:
This session intends to cover the state-of-the-art in mammalian, plant, algal and insect cell culture toward the production of biofuels, therapeutics and high-value secondary metabolites. This session will focus on phenotype characterization using metabolic flux analysis and metabolomics, and the development of mathematical models towards prediction and control of cell culture behavior on small and large scales.

Sponsor:
Bioengineering


Chair:
Ganesh Sriram
Assistant Professor
University of Maryland
Chemical and Biomolecular Engineering
1208D Chemical and Nuclear Engr. Bldg. 090
College Park, MD 20742
Phone Number: 301-405-1261
Fax Number: 301-405-0523
Email: gsriram@umd.edu

Co-Chair:
An Zhang
Biogen Idec
5200 Research Place
San Diego, CA 92122
Phone Number: 614-256-9550
Email: an.zhang@biogenidec.com


Papers:
Elucidation of Perturbed Gluconeogenesis Flux in Fao Rat Hepatoma Cell Line Using Multiple Isotopic Tracers
Maciek R. Antoniewicz, Univerisity of Delaware; Woo Suk Ahn, University of Delaware
Role of Anti-Apoptotic Proteins and Nutrient Availability in the Lactate Shift of CHO Cell Cultures
Neil Templeton, Vanderbilt University; J.D. Young, Vanderbilt University
Metabolic Flux Analysis and Proteomics of CHO Cell Culture During Growth and Recombinant Protein Production
Neelanjan Sengupta, Purdue University; John A. Morgan, Purdue University
A Model for Long-Term Dynamic Simulation of Cell Metabolism
Ryan P. Nolan, Tufts University; Kyongbum Lee, Tufts University
Modelling Photoacclimation
Jose C. Merchuk, Ben-Gurion University; Francisco Garcia-Camacho, Universidad de Almeria; Emilio Molina-Grima, Universidad de Almeria
Towards Online Control of Protein Glycosylation: Establishing Nutrient Setpoint Control in Bioreactors
Melissa M. St. Amand, University of Delaware; Anne S. Robinson, University of Delaware; Babatunde A. Ogunnaike, University of Delaware
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division