Session: Advances in Protein Structure, Function, and Stability I (2010 Annual Meeting)

Description:

We invite submissions pertaining to protein structure, function, and stability. Studies may include structural or functional analysis, engineering of new proteins, analysis of protein conformational and colloidal stability, mechanisms of protein folding and misfolding, and mechanisms of protein degradation via physical and chemical routes. Reports relevant to other biotechnological products are also welcome.

Sponsor:

Bioengineering

Chair:

Peter M. Tessier
Assistant Professor
Rensselaer Polytechnic Institute
Dept of Chemical & Biological Engineering
Troy, NY 12180
Phone Number: 518-276-2045
Email: tessier@rpi.edu

Co-Chair:

Sheldon Park
State University of New York at Buffalo
Chemical Eng.
905 Furnas Hall
Buffalo, NY 14260
Phone Number: 7166451199
Email: sjpark6@buffalo.edu

Papers:

575a

Length and Location: What Matters Most in PolyQ Protein Aggregation
Regina M. Murphy, University of Wisconsin; Matthew D. Tobelmann, University of Wisconsin

575b

β Sheet Not Prevalent in Amyloid Nucleus
Caryn L. Heldt, Rensselaer Polytechnic Institute; Dmitry Kurouski, University at Albany, SUNY; Mirco Sorci, Rensselaer Polytechnic Institute; Elizabeth Grafeld, Rensselaer Polytechnic Institute; Igor K. Lednev, University at Albany, SUNY; Georges Belfort, Rensselaer Polytechnic Institute

575c

Polyphenols Do Not Disassociate Alzheimer's Disease Amyloid-β Fibrils but Bind Fibrils to Interrupt Fibril-Thioflavin T Interactions
Chen Suo, University of South Carolina; Jui-Heng Tseng, University of South Carolina; Laying Wu, University of South Carolina; Qian Wang, University of South Carolina; Melissa A. Moss, University of South Carolina, Columbia

575d

Curcumin Offers Neuroprotection by Inhibiting Amyloid-Beta Insertion Into Membranes
Arjun Thapa, University of New Mexico; Briana Givler, University of New Mexico; Eva Chi, University of New Mexico

Intermission

575e

Antibody Adsorption and Orientation On Hydrophobic Surfaces
Meredith E. Wiseman, Stanford University; Curtis W. Frank, Stanford University

575f

The Use of Low Melting Point Organic Salts as Excipients to Increase Protein Stability in Solution
Gloria D. Elliott, University of North Carolina at Charlotte; Katherine Weaver, University of North Carolina at Charlotte; Regina M. Vrikkis, University of North Carolina at Charlotte; Jonathan Trullinger, University of North Carolina at Charlotte; Karen Thorsett-Hill, University of North Carolina at Charlotte; Ranganathan Vijayaraghavan, Monash University; Douglas MacFarlane, Monash University; Joanna Krueger, University of North Carolina at Charlotte

575g

Investigating Aglycosylated Antibody Stability and Retention On Cation Exchange Chromatography
David M. Glover, Genentech

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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