Session: Bioseparations and Downstream Processing (2010 Annual Meeting)

Description:

This session will focus on highlighting the latest advances in downstream processing relevant to purification/polishing operations including rapid process development, improved efficiency, cost reduction, integration of operations, handling of high titre streams and sustainability issues. Topics to be covered include, but are not limited to: Uni- and multi-modal chromatography, membrane-based separations and filtration, extraction, precipitation and crystallization.

Sponsor:

Bioengineering

Co-Sponsor(s):

Separations Division (02)

Chair:

Todd M. Przybycien
Professor
Carnegie Mellon University
Department of Chemical Engineering and Department of Biomedical Engineering
Pittsburgh, PA 15213
Phone Number: 412-268-9808
Fax Number: 412-268-9807
Email: todd@andrew.cmu.edu

Co-Chair:

David Wood
Associate Professor
Ohio State University
Department of Chemical and Biomolecular Enginnering
435 Koffolt Laboratories
Columbus, OH 43210
Phone Number: 614-292-9636
Email: wood@chbmeng.ohio-state.edu

Papers:

204b

Depth Filter Train Optimization of a High Cell Density Product Stream
Jessica R. Molek, GlaxoSmithKline; Andrea S. Deiner, GlaxoSmithKline; Hiren D. Ardeshna, GlaxoSmithKline; Andrew D. Weber, GlaxoSmithKline; Kent E. Goklen, GlaxoSmithKline

204c

A Comparison of Convective-Based Alternatives to Packed Bed Affinity Chromatography for the Purification of Monoclonal Antibodies
Cristiana Boi, University of Bologna; Simone Dimartino, University of Bologna; M. Omon Herigstad, University of Bologna; Giulio C. Sarti, University of Bologna

204d

Design of a Scalable Continuous Precipitation Process for the High Throughput Capture and Purification of High Titer Monoclonal Antibodies
Orlando A. Jaquez, Biogen Idec; Robert S. Gronke, Biogen Idec; Todd M. Przybycien, Carnegie Mellon University

204e

Clustered-Charge Anion Exchange Adsorbents: Nucleic Acid Affinity and Single-Molecule Characterization
Wen-hsiang Chen, University of Houston; Mohan Vivekanandan Poongavanam, University of Houston; Richard C. Willson, University of Houston

204f

Prediction and Optimization of Chromatographic Performance Using High Throughput 96-Well Plates
Nooshafarin Sanaie, Biogen Idec; James Ware, Biogen Idec; John Pieracci, Biogen Idec; Justin Mccue, Biogen Idec

204g

BSA Purification with Continuous Annular Chromatography
Gonca Saglam, Hacettepe University; Gönül Akkaya, Hacettepe University; Yasemin Onaran, Hacettepe University; Ece Mindek, Hacettepe University; Deniz Tanyolaç, Hacettepe University; Ahmet R. Özdural, Hacettepe University

204h

Small-Molecular Foldase Mimics Facilitating Oxidative Protein Refolding
Guo-Zhen Wang, Tianjin University; Xiao-Yan Dong, Tianjin University; Yan Sun, Tianjin University

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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