Session: Protein Engineering II - Techniques (2010 Annual Meeting)

Description:

The focus of this session is to reflect the latest advances in protein engineering and design. Suggested topics include, but are not limited to: (1) Development of high throughput screen/selection for protein engineering; (2)Development of novel protein engineering methods; (3) protein engineering via directed evolution; (4) computational protein engineering and design.

Sponsor:

Bioengineering

Chair:

Inchan Kwon
Assistant Professor
University of Virginia
Chemical Engineering
Charlottesville, VA 22904
Phone Number: 434-924-7778
Email: ik4t@virginia.edu

Co-Chair:

Danielle Tullman-Ercek
Assistant Professor
University of California Berkeley
Chemical Engineering
201 Gilman Hall
Berkeley, CA 94720
Phone Number: 5106427160
Email: dtercek@berkeley.edu

Papers:

119a

An in Vitro Platform to Evolve Proteins Directly for Improved Biological Function
Bertrand H. Lui, Stanford University; Jennifer R. Cochran, Stanford University; James R. Swartz, Stanford University

119b

Epitope Expansion Evolution for the Affinity Maturation of Ligand-Receptor Interactions
Douglas S. Jones, Stanford University; Mihalis S. Kariolis, Stanford University; Jennifer R. Cochran, Stanford University

119c

Engineering High-Affinity Antibodies Using Inner Membrane Display of Translocation Intermediates
Amy J. Karlsson, Cornell University; Hyung-Kwon Lim, Cornell University; Mark A. Rocco, Cornell University; Matthew P. DeLisa, Cornell University

119d

The Deg-On System: Generation of a Cell-Based High Throughput Assay for the Screening of Proteasome Activators
Wenting Zhao, Rice University; Laura Segatori, Rice University

Break

119e

Efficient Screening of Natural Fungal Cellobiohydrolase Genes for Desirable Mutations by SCHEMA Structure-Guided Recombination
Pete Heinzelman, California Institute of Technology; Russell Komor, California Institute of Technology; Arvind Kanaan, California Institute of Technology; Philip Romero, California Institute of Technology; Xinlin Yu, California Institute of Technology; Shannon Mohler, California Institute of Technology; Christopher D. Snow, California Institute of Technology; Frances H. Arnold, California Institute of Technology

119f

De Novo Protein Design of a Conformational Switch Between α-Helical Protein and Mixed α/β Protein
James Smadbeck, Princeton University; Meghan L. Bellows, Princeton University; Yuhong Liu, Princeton University; Christodoulos A. Floudas, Princeton University

119g

Computational Analysis of the Protein Sequence Space: A New Method to Identify Beneficial Mutations
Prabuddha Bansal, Georgia Institute of Technology; Mélanie Hall, Georgia Institute of Technology; Matthew Realff, Georgia Institute of Technology; Jay H. Lee, Georgia Institute of Technology; Andreas S. Bommarius, Georgia Institute of Technology

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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