Session: PAT for Crystallization Development and Manufacturing (2010 Annual Meeting)

Description:

This session welcomes presentations on recent applications of Process Analytical Technologies (PAT) for development and manufacturing of crystallization processes. PAT applications may include various spectroscopy (FTIR, NIR, Raman), particle size and counting techniques (FBRM, PVM), and other on-line or in-line monitoring or sensing techniques. Novel approaches and methodologies to drive crystallization development are of particular interest.

Sponsor:

Crystallization and Evaporation

Co-Sponsor(s):

Process Research and Innovation (12a), Pharmaceuticals (15b)

Chair:

Levente L. Simon
Senior Researcher
ETH Zurich
Institute for Chemical and Bioengineering
G-138, HCI, ETH Hoenggerberg
Zurich 8093
Phone Number: 0041134486
Email: levente.simon@chem.ethz.ch

Co-Chair:

Jean Tom
Bristol-Myers Squibb Company
Process Research & Development
One Squibb Drive
New Brunswick, NJ 08903
Phone Number: 732-227-5408
Email: jean.tom@bms.com

Papers:

355a

Real-Time Monitoring of Nucleation and Growth Rates in An Industrial Semi-Batch Sugar Crystallizer
Terry P. Redman, METTLER TOLEDO AutoChem; Greg Golovanoff, Amalgamated Sugar Company; Wayne Genck, Genck International

355c

Apply PAT to the Definition of Design Space to Enable the Control Strategy for Crystallization Processes
George Zhou, Merck & Co., Inc.; Aaron Moment, Merck & Co., Inc.; Angela Spartalis, Merck & Co., Inc.; Sean Harrington, Merck & Co., Inc.; Shane Grosser, Merck & Co., Inc.; Marguerite Mohan, Merck & Co., Inc.; Naijun Wu, Merck & Co., Inc.; Ganeshwar Prasad, Merck & Co., Inc.; Tseng-En Hu, Merck & Co., Inc.; Paul Fernandez, Merck & Co., Inc.; John Higgins, Merck & Co., Inc.

355d

Automated Crystallization Platform: Integrating Hardware, Software, and PAT to Expedite the Process of Crystallization Development
Amanda Rogers, Bristol-Myers Squibb Co; Jacob Albrecht, Bristol-Myers Squibb Co; James Vernille, Bristol-Myers Squibb Co; Jose Tabora, Bristol-Myers Squibb Co; Francesco Ricci, Princeton University; Mitsuko Fujiwara, University of Illinois at Urbana-Champaign; Richard D. Braatz, Massachusetts Institute of Technology

355e

Characterization of Flash Crystallization Process Using PAT
Barbara Wood, University College Dublin; Brian Glennon, University College Dublin

355f

Crystallization Scale-up with Process Analytical Technologies – Ensuring Success From the R&D Lab to the Manufacturing Plant
Terry P. Redman, METTLER TOLEDO AutoChem; Ben Smith, METTLER TOLEDO AutoChem; Des O'Grady, METTLER TOLEDO AutoChem

355g

Direct Measurement of Length and Orientation of Microfibers in Solution
Taslima Khanam, Nanyang Technological University; Nurur Rahman Mohammad, Nanyang Technological University; Arvind Rajendran, Nanyang Technological University; Vinay Kariwala, Nanyang Technological University; Anand K. Asundi, Nanyang Technological University

See more of this Group/Topical: Separations Division

<< Previous Session | Next Session >>