This preliminary program is subject to change.

Systems and Synthetic Biology of Interacting Microorganisms


Description:
Microorganisms (viruses, bacteria, and fungi) play critical roles in numerous natural processes associated with human health and the environment. Almost without exception, these microbes are engaged in extensive interactions with one another and/or with other species (e.g., their human host). With the rapid development of high throughput technologies (e.g., metagenomic sequencing) and related computational methods, the investigation of microbe-microbe and microbe-host interactions are defining new frontiers of systems biology. Moreover, emerging synthetic biology approaches have also started to capitalize on this research area of rich potential. This session will highlight original systems and synthetic biology approaches for understanding and engineering microbial interactions. Topics of interest include, but are not limited to: "omics" based study of microbial communities; modeling of microbe-host interactions; synthetic systems of interacting microbes; and engineering of microbial consortia. Subjects closely related to practical applications (e.g., challenges in the environment or human health) are especially of interest.

Sponsor:
Bioengineering
Co-Sponsor(s):
Topical A: Systems Biology (TA)


Chair:
Xiaoxia (Nina) Lin
Assistant Professor
The University of Michigan at Ann Arbor
Chemical Engineering
2300 Hayward St., 3074 HH Dow Bldg.
Ann Arbor, MI 48109
Phone Number: 734-647-8026
Email: ninalin@umich.edu

Co-Chair:
Lingchong You
Duke University
Biomedical Engineering
Durham, NC 27708
Phone Number: 919-660-8408
Fax Number: 919-668-0795
Email: you@duke.edu


Papers:
67a
Host Genetic Interactions During Viral Infection: A Systems Virology Approach to Lambda Phage Infection of E. Coli
Elsa Birch, Stanford University; Nathaniel Maynard, Stanford University; Markus Covert, Stanford University
67c
Community Modeling and the Design of Effective Uranium Bioremediation Strategy
Kai H. Zhuang, University of Toronto; Eugene Ma, University of Toronto; Melissa Barlett, Department of Microbiology, University of Massachusetts, Amherst; Derek R. Lovley, Department of Microbiology, University of Massachusetts, Amherst; Radhakrishnan Mahadevan, University of Toronto
67d
Quantitative Proteomic Analysis of Interactions in a Binary Bacterial Culture
Kenneth F. Reardon, Colorado State University; Carla M. R. Lacerda, Colorado State University
67e
Dynamic Flux Balance Modeling of a Microbial Co-Culture for Efficient Batch Fermentation of Glucose and Xylose Mixtures
Timothy Hanly, University of Massachusetts; Morgan Urello, Columbia University; Michael A. Henson, University of Massachusetts
67f
Tunable Synthetic Microbial Consortia: Foundations and Applications
Alissa R. Kerner, University of Michigan; Xiaoxia (Nina) Lin, University of Michigan
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division