Session: Receptor-Mediated Phenomena (2010 Annual Meeting)

Description:

Cells sense and respond to their environment via receptor-mediated phenomena. In this session, we encourage talks that highlight spatial and dynamic aspects of receptor events, including the interplay between receptor trafficking and intracellular signaling, the coupling of mechanical stresses with cell signaling, receptor regulation, receptor-mediated therapeutic strategies, and cross-talk among receptor signaling pathways. Examples that integrate experiments with theory are particularly welcome.

Sponsor:

Engineering Fundamentals in Life Science

Chair:

Matthew J. Lazzara
University of Pennsylvania
Chemical and Biomolecular Engineering
311A Towne Building
Philadelphia, PA 19104-6393
Phone Number: 215-746-2264
Email: mlazzara@seas.upenn.edu

Co-Chair:

Joshua N. Leonard
Assistant Professor
Northwestern University
Chemical and Biological Engineering
2145 Sheridan Rd.
Evanston, IL 60208-3120
Phone Number: 847-491-7455
Fax Number: 847-491-3728
Email: j-leonard@northwestern.edu

Papers:

49a

Tuning Capillary Network Formation with Bioactive Motifs in a 3D Matrix
John J. Schmidt, University of Illinois at Urbana-Champaign; Hyun Joon Kong, University of Illinois at Urbana-Champaign

49b

Integrated Feedback Regulation of the Epidermal Growth Factor Receptor in Non-Small Cell Lung Cancer
Alice J. Macdonald, University of Pennsylvania; Matthew J. Lazzara, University of Pennsylvania

49c

Killing Metastatic Cancer Cells Using Immobilized TRAIL and E-Selectin: Combined Treatment with Chemotherapeutics
Kuldeepsinh Rana, Cornell University; Cynthia A Reinhart-King, Cornell University; Jane L. Liesveld, University of Rochester; Michael R King, Cornell University

49d

Regulation of the Recognition of Pattern Recognition Receptors by Nanoparticles
Helen C. Chen, University of Washington, Seattle; Hong Shen, University of Washington

Break

49e

Biophysical Characterization of CD44v-Counter Receptor Interactions Using Force-Spectroscopy
Phrabha Shalini Raman, Johns Hopkins University; Christina S. Alves, Johns Hopkins University; Denis Wirtz, Johns Hopkins University; Konstantinos Konstantopoulos, Johns Hopkins University

49f

Engineered Hepatocyte Growth Factor Fragments Function as Met Receptor Antagonists by Inhibiting Ligand-Induced Dimerization
Douglas S. Jones, Stanford University; Jennifer R. Cochran, Stanford University

49g

Effects of Convective Flow On Chemical Signaling in Cellular Systems
Michal Pribyl, Institute of Chemical Technology; Petr Cervenka, Institute of Chemical Technology; Otto Hadac, Institute of Chemical Technology; Igor Schreiber, Institute of Chemical Technology

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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