Session: Synthetic Systems Biology II (2010 Annual Meeting)

Description:

Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest.

Sponsor:

Topical A: Systems Biology

Chair:

Lingchong You
Duke University
Biomedical Engineering
Durham, NC 27708
Phone Number: 919-660-8408
Fax Number: 919-668-0795
Email: you@duke.edu

Co-Chair:

Joshua N. Leonard
Assistant Professor
Northwestern University
Chemical and Biological Engineering
2145 Sheridan Rd.
Evanston, IL 60208-3120
Phone Number: 847-491-7455
Fax Number: 847-491-3728
Email: j-leonard@northwestern.edu

Papers:

125a

Engineering T-Cell Receptor Signaling Dynamics for Cell-Based Immunotherapy
Wilson W. Wong, University of California, San Francisco; Ethan Corcoran, University of California, San Francisco; Arthur Weiss, University of California, San Francisco; Lim Wendell, University of California, San Francisco

125b

Directed Evolution of Quorum-Sensing Dependent Transcriptional Repressors for Programmed Intercellular Communication
Jasmine Shong, Rennselaer Polytechnic Institute; Cynthia H. Collins, Rennselaer Polytechnic Institute

125c

Novel, Synthetic, Tetracycline-Inducible Transcription Regulators for E. Coli
Katherine G. Volzing, University of Minnesota; Yiannis N. Kaznessis, University of Minnesota

125d

Model-Driven Minimization of the B. Subtilis Genome
Christopher Henry, Argonne National Laboratory; Kosei Tanaka, INRA; Jenifer Zinner, Argonne National Laboratory; Matthew Cohoon, Argonne National Laboratory; Rick Stevens, Argonne National Laboratory; Philippe Noirot, INRA

125e

A Microrna Based Synthetic Network as Stable Expression Unit in Mammalian Cells
Leonidas Bleris, Harvard University; Zhen Xie, Harvard University; Eduardo Sontag, Rutgers University; Yaakov Benenson, Harvard University

125f

Systematic Reduction of Models of Mechanistic Template Polymerization Processes and Applications to Genetic Networks
Vassily Hatzimanikatis, Ecole Polytechnique Fédérale de Lausanne (EPFL); Luis Mier-y-Teran R, Northwestern University; Mary Silber, Northwestern University

See more of this Group/Topical: Topical A: Systems Biology

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