This preliminary program is subject to change.

Synthesis, Characterization and Modeling of Nanoparticle Systems with Pharmaceutical Applications


Description:
In the past decade, the poor water-solubility of many drugs has become a focal point of the pharmaceutical industry. In addition, it has also driven the innovation of several novel techniques to administer safe and effective drug levels. Nanoparticles have been proven to achieve a faster solubility rate, and thus, a higher bioavailability of the drug. Furthermore, nanoparticles exhibit many other unique advantages for drug delivery including: passive targeting, ease of suspension, variable optical properties, and the ability to be functionalized. This session welcomes papers focused on the synthesis, characterization, stabilization and modeling of nanoparticle systems with pharmaceutical applications. A particular focus of this section is given to the interactions with polymers and surfactants and contributions to mechanisms of stabilization and drug delivery.

Sponsor:
Nanoparticles


Chair:
Maria. S Tomassone
Rutgers University
Department of Chemical and Biochemical Engineering
98 Brett Road
Piscataway, NJ 08854
Phone Number: 732-445-2972
Email: silvina@soemail.rutgers.edu

Co-Chair:
Rajesh Dave
New Jersey Institute of Technology
Mechanical Engineering Department, YCEES 208
Newark, NJ 07102
Phone Number: 973 596 5860
Fax Number: 973 642 7088
Email: dave@NJIT.EDU


Papers:
Crystallization Behaviour and Structural Characterization of Drug/Polymer Solid Dispersions
Qing Zhu, Purdue University; Michael Harris, Purdue University; Lynne Taylor, Purdue University
Optimizing the Coating of Microparticles with Nanoparticles at Higher Microparticle Concentrations
Kapil V. Deshpande, Rutgers University; Nina Shapley, Rutgers University
Challenges of Polymorphism Changes On Drug Substance and Drug Product Process Development - Case Study
Richard Schild, Bristol-Myers Squibb Company; Daniel Hallow, Bristol-Myers Squibb Company; Chiajen J Lai, Bristol-Myers Squibb Company; Qi Gao, Bristol-Myers Squibb Company; Amol Mungikar, Bristol-Myers Squibb Company; Renče Randazzo, Bristol-Myers Squibb Company; Roxana Schlam, Bristol-Myers Squibb Company; Chris Sfouggatakis, Bristol-Myers Squibb Company; Chenchi Wang, Bristol-Myers Squibb Company
Synthesis and Characterization of Hyperbranched and Dendritic Poly(N-isopropylacryalmide) with Physiological Transition Temperatures for Targeted Drug Delivery
Kai Chang, Georgia Institute of Technology; Lindsey A Bergman, Georgia Institute of Technology; Lakeshia J. Taite, Georgia Institute of Technology
The Influence of Polymer Properties On the Inhibition of Crystallization
Michael Tomasini, Rutgers University; M. Silvlna Tomassone, Rutgers University
Engineered Particles Prepared Via Drying of Drug Nanosuspensions for Bioavailability Enhancement
Anagha Bhakay, New Jersey Institute of Technology; Mohammad Azad, New Jersey Institute of Technology; Ecevit Bilgili, New Jersey Institute of Technology; Rajesh Davé, New Jersey Institute of Technology
Surface Characterization of Aspirin Crystal Planes in the Presence of Polymers, Surfactants, and Solvents
Wusheng Zhu, Rutgers University; Frank Romanski, Rutgers University; M. Silvina Tomassone, Rutgers University
See more of this Group/Topical: Particle Technology Forum