Session: Experimental Approaches in Systems Biology II (2010 Annual Meeting)

Description:

This session focuses on the latest advances in applied experimental approaches for understanding biological networks. We invite submissions on topics that involve techniques for measuring and manipulating cells and tissues at the genomic, transcriptomic, proteomic or metabolomic levels, as well as novel methods to study regulatory interactions among these levels. Topics of particular interest include, but are not limited to: mRNA expression analysis; studies on small RNAs and their roles in gene regulation; gene translation analysis; protein identification and functional studies for transcriptional networks; flux analysis and metabolomic profiling of tissues/organs; and integrated single-cell analyses for mapping signaling networks.

Sponsor:

Engineering Fundamentals in Life Science

Chair:

J. Christopher Love
Asst. Professor
Massachusetts Institute of Technology
Chemical Engineering
77 Massachusetts Ave., Bldg. 66-456
Cambridge, MA 02139
Phone Number: 617-324-2300
Email: clove@mit.edu

Papers:

536a

Metabolic Flux Analysis in E. Coli Using Tandem Mass Spectrometry
Maciek R. Antoniewicz, Univerisity of Delaware; Jungik Choi, Univerisity of Delaware

536b

Uncoupling of Central Metabolism Is Responsible for Palmitate-Induced ROS Accumulation and Hepatic Apoptosis
Robert Egnatchik, Vanderbilt University; J.D. Young, Vanderbilt University

536c

Impact of Nutritional Stress and Liver Metabolic State On Xenobiotic Drug Transformation and Hepatotoxicity
Gautham V. Sridharan, Tufts University; Katherine A. Carson, Tufts University; Michael Yi, Tufts University; Kyongbum Lee, Tufts University

536d

Quantification of Multiple Microrna Levels Using Molecular Affinity Isolation and Mass Spectrometry
Daniel S. Duffield, Rutgers University; Sobin Kim, Rutgers University

Break

536e

Transcriptome Analysis of Chlamydomonas Reinhardtii During Nitrogen Starvation Using RNAseq
Nanette R. Boyle, University of California, Los Angeles; David Casero, University of California, Los Angeles; Matteo Pellegrini, University of California, Los Angeles; Sabeeha S. Merchant, University of California, Los Angeles

536f

Function-Based Screening of HIV-Specific CD8 T Cells Using Arrays of Subnanoliter Wells
Navin Varadarajan, University of Houston; Boris Julg, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard; Douglas Kwon, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard; Adebola Ogunniyi, Massachusetts Institute of Technology; Bjorn Nilsson, Broad Institute; Bruce D. Walker, Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard; J. Christopher Love, Massachusetts Institute of Technology

536g

Microfluidic Chamber Arrays for High-Throughput Combinatorial Screening
Kwanghum Chung, Gatech; Emily S. Gong, Georgia Institute of Technology; Hang Lu, Georgia Institute of Technology

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division

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