110 Protein Engineering II - Techniques

Monday, October 29, 2012: 12:30 PM
Fayette (Westin )
Description:
The focus of this session is to reflect the latest advances in protein engineering and design. Suggested topics include, but are not limited to: (1) Development of high throughput screen/selection for protein engineering; (2)Development of novel protein engineering methods; (3) protein engineering via directed evolution; (4) computational protein engineering and design.

Sponsor:
Bioengineering

Chair:
Bradley C. Bundy
Email: bundy@byu.edu

Co-Chair:
Karl E. Griswold
Email: Karl.E.Griswold@Dartmouth.edu


12:30 PM
(110a) A Platform for Antibody Engineering Against Membrane Protein Targets Using Detergent-Solubilized Cell Lysates As Antigen Sources
Yong Ku Cho, Ben J. Tillotson, Inigo de Larrinoa and Eric V. Shusta

12:48 PM
(110b) Directed Evolution Strategies for Escaping Local Fitness Maxima
Barrett Steinberg and Marc Ostermeier

1:06 PM
(110c) Enhancing FLI-TRAP for Rapid Isolation of Solubility and Affinity Matured Antibodies
Dujduan Waraho and Matthew P. DeLisa

1:24 PM
(110d) Development of a High-Throughput Screen for Directed Evolution of Inteins
Michael J. Coolbaugh and David W. Wood

1:42 PM
(110e) Mod Designer: A Robust Optimization Framework for the Design of Proteins with Post-Translational Modifications and Unnatural Amino Acids and Its Applications to Cancer
George A. Khoury, James Smadbeck and Christodoulos A. Floudas

2:00 PM
(110f) A Novel Amine Dehydrogenase for the Selective Production of Chiral Amines
Michael J. Abrahamson, Eduardo Vazquez-Figueroa, Nicholas Woodall, Jeffery Moore and Andreas S. Bommarius

2:18 PM
(110g) A Platform for the Discovery of Proteasomal Degradation Activators
Wenting Zhao and Laura Segatori

2:36 PM
(110h) Quantitative Functional Single-Cell Characterization of Surface Display of Recombinant Proteins Using A Bacterial Autotransporter
Balakrishnan Ramesh, Patrick C. Cirino and Navin Varadarajan
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture
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