This preliminary program is subject to change.

Modeling Approaches for Biological Phenomena


Description:
We invite submissions that describe the application of mathematical modeling to problems in the life sciences. Suggested topics include, but are not limited to, metabolism, signal transduction, and gene regulation. Preference will be given to submissions that directly link mathematical modeling with experimental data. Submissions that describe novel modeling approaches are also encouraged.

Sponsor:
Bioengineering
Co-Sponsor(s):
Topical A: Systems Biology (TA)


Chair:
Mark P. Brynildsen
Assistant Professor
Princenton University
Chemical and Biological Engineering
Princeton, NJ 08544
Email: mbrynild@Princeton.EDU

Co-Chair:
Mariajose Castellanos
Assistant Professor
UMBC
Chemical and Biochemical Engineering
1000 Hilltop Circle
Baltimore, MD 21250
Fax Number: 410-455-1049
Email: mariajose@umbc.edu


Papers:
A Systems-Level Analysis Approach for Identifying Genetic Targets to Treat Biofilm-Forming Pathogens: An Application to Pseudomonas Aeruginosa
Zhaobin Xu, Villanova University; Xin Fang, Henry M. Jackson Foundation; Thomas K. Wood, Pennsylvania State University; Zuyi (Jacky) Huang, Villanova University
Engineering ROS Metabolism with Futile Cycles
Kristin Adolfsen, Princeton University; Mark P. Brynildsen, Princenton University
Dynamic Modelling As a Tool for Increasing Single-Chain Antibody Fragment Specific Productivity in Pichia Pastoris
Kate Royle, Imperial College London; David Leak, University of Bath; Cleo Kontoravdi, Imperial College London
Modeling Intra- and Inter-Kingdom Signaling Through NF-Kb Pathway in Dendritic Cells
Shreya Maiti, Texas A&M University; Robert Alaniz, Texas A&M Health Science Center; Juergen Hahn, Rensselaer Polytechnic Institute; Arul Jayaraman, Texas A&M University
Optimum Perfusion Duration for Machine-Perfused Rat Livers
Sinem Perk, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospital for Children; Maria-Louisa Izamis, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospital for Children; Herman Tolboom, University Hospital Zurich; Basak Uygun, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospital for Children; Francois Berthiaume, Rutgers, The State University of New Jersey; Martin L. Yarmush, MGH/Harvard Medical School; Korkut Uygun, Center for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, Shriners Hospital for Children
Analysis of EGFR Flux Through Different Endocytic Pathways in Cancer Cells with Elevated EGFR Expression
Alice J. Macdonald, University of Pennsylvania; Matthew J. Lazzara, University of Pennsylvania
A Stochastic Model of Glycosylation of Monoclonal Antibodies
Devesh Radhakrishnan, University of Delaware; Andrew Bitner, University of Delaware; Melissa St. Amand, University of Delaware; Kevin Tran, University of Delaware; Anne S. Robinson, University of Delaware; Babatunde A. Ogunnaike, University of Delaware