This preliminary program is subject to change.

Protein Engineering IV - Applications


Description:
Protein engineering has wide application areas ranging from basic science to industrial production and disease therapy. For this session, we invite high-quality presentations that reflect the latest advances in protein engineering and applications. Potential topics include, but are not limited to: protein-based biosensors and actuators, protein ligand/receptor engineering, protein-based biomaterials, development of novel protein fusion partners, and novel antibody engineering.

Sponsor:
Bioengineering


Chair:
Yvonne Chen
Junior Fellow
Harvard Society of Fellows
78 Mt. Auburn Street
Cambridge, MA 02138
Email: yvonne_chen@hms.harvard.edu

Co-Chair:
Basar Bilgicer
Assistant Professor
University of Notre Dame
Chemical and Biomolecular Engineering
165 Fitzpatrick Hall
Notre Dame, IN 46556
Fax Number: (574) 631-8366
Email: bbilgicer@nd.edu


Papers:
A Rapid Approach to the Development of Affinity Reagents Using Yeast Surface Display
James A. Van Deventer, Massachusetts Institute of Technology; Sachdev Sidhu, University of Toronto; K. Dane Wittrup, Massachusetts Institute of Technology
Cloning Nuclear Hormone Receptors to Develop Biosensors Using the Gibson Assembly
Miriam Shakalli Tang, Ohio State University; Richard A. Lease, Ohio State University; David Wood, Ohio State University
Engineering Cystine Knot Peptides As a New Class of Molecular Imaging Agents
Cheuk Lun Leung, Stanford University; Sarah J. Moore, Stanford University; Heidi Norton, Stanford University; Jennifer R. Cochran, Stanford University
Engineering Hetero-Bivalent Peptidic Ligands to Inhibit Mast Cell Degranulation in a Heterotetravalent Allergy Model
Michael W. Handlogten, University of Notre Dame; Tanyel Kiziltepe, University of Notre Dame; Basar Bilgicer, University of Notre Dame
Targeted Drug Delivery to the Brain Using Transferrin-Binding Peptides
Divya Chandra, Rensselaer Polytechnic Institute; Pankaj Karande, Rensselaer Polytechnic Institute
Engineered Monobody Inhibitors of Erk-2 Dependent Signaling
Jasdeep Mann, State University of New York at Buffalo; Anne-Fleur Stephan, State University of New York at Buffalo; Jordan Wood, State University of New York at Buffalo; Denise Ferkey, State University of New York at Buffalo; E. Manolis Tzanakakis, State University of New York at Buffalo; Sheldon Park, State University of New York at Buffalo
Structure-Based Design of Antibodies Specific for Misfolded Proteins
Joseph M. Perchiacca, Rensselaer Polytechnic Institute; Moumita Bhattacharya, Rensselaer Polytechnic Institute; Ali Reza A. Ladiwala, Rensselaer Polytechnic Institute; Swarnim Ranjan, Rensselaer Polytechnic Institute; Peter M. Tessier, Rensselaer Polytechnic Institute