This preliminary program is subject to change.

Metabolic Engineering and Bioinformatics


Description:
Metabolic engineering is the targeted improvement of the cellular metabolic phenotype using recombinant DNA technology. Improvements often require characterization of the existing and heterologous metabolic networks using both experimental and computational techniques. Abstracts describing new developments in these topics are sought, and those incorporating both mathematical modeling and experimental aspects are particularly encouraged. Example areas include quantification of metabolic fluxes, inverse metabolic engineering, production of novel products, application of evolutionary techniques, construction of metabolic models from genomic data, and incorporation of microarray and proteomic data and mathematical modeling of metabolism. The session is open to papers focused on any type of organism.

Sponsor:
Bioengineering


Chair:
Chase L. Beisel
Assistant Professor
North Carolina State University
Department of Chemical and Biomolecular Engineering
911 Partners Way
Raleigh, NC 27695-7905
Fax Number: 919-515-3465
Email: cbeisel@ncsu.edu

Co-Chair:
Keith E.J. Tyo
Assistant Professor
Northwestern University
Chemical and Biological Engineering
Evanston, IL Fax Number: +46(0)31 772 3801
Email: k-tyo@northwestern.edu


Papers:
96a
Engineering Escherichia Coli for Adipic Acid Production
Yuanqing Wu, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences; Wujiu Chen, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences; Yuanyuan Zhang, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences; Li Han, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences; Yanfeng Peng, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences; Ran Tu, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences; Qinhong Wang, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences; Yanhe Ma, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
96b
Metabolic Engineering of Escherichia Coli K5 for Production of Heparosan, a Precursor to the Anticoagulant Pharmaceutical Heparin
Brady Cress, Rensselaer Polytechnic Institute; Mattheos A.G. Koffas, Rensselaer Polytechnic Institute; Robert J. Linhardt, Rensselaer Polytechnic Institute
96c
Reusable Pathway Optimization with Quantitative Sequence-Expression-Flux Maps
Iman Farasat, Pennsylvania State University; Jason Collens, Pennsylvania State University; Howard Salis, Pennsylvania State University
96d
Ctfab and adhE2 Can Induce Acetone Production and Increase Butanol Production Yield From Glucose in Clostridium Tyrobutyricum
Le Yu, The Ohio State University; Jingbo Zhao, The Ohio State University; Shang-Tian Yang, Ohio State University
96e
Engineering Auto-Regulatory Genetic Circuits for Production of Hydroxycinnamic Acid-Derived Chemicals
Tat-Ming Lo, Nanyang Technological University; Chueh Loo Poh, Nanyang Technological University; Matthew Wook Chang, Nanyang Technological University
96f
Metabolic Engineering of Escherichia Coli for Production of Mcl-PHA From Unrelated Carbon Sources
Daniel E. Agnew, University of Wisconsin - Madison; J. Tyler Youngquist, University of Wisconsin Madison; Brian F. Pfleger, University of Wisconsin Madison
96g
Expanding the Synthetic Biology Toolbox for Engineering Metabolic Pathways in E. Coli
Peng Xu, Rensselaer Polytechnic Institute; Mattheos A.G. Koffas, Rensselaer Polytechnic Institute
96h
Metabolic Engineering of Escherichia Coli for (2S)-Pinocembrin Production From Glucose
Jingwen Zhou, Jiangnan University; Junjun Wu, Jiangnan University; Guocheng Du, Jiangnan University; Jian Chen, Jiangnan University