Session: Cell Culture I: Experimental (2012 Annual Meeting)

Description:

This session intends to cover the state-of-the-art in mammalian, plant, algal and insect cell culture toward the production of biofuels, pharmaceuticals, vaccines and high-value secondary metabolites. Topics for this session focus on experimental methods which include, but are not limited to, cell line development and engineering, genomics, metabolomics and proteomics analysis, high throughput cell culture screening systems, media development, bioreactor design and operation scale-up and scale-down methodologies, improvement of yield recombinant protein or vaccines yield through process optimization, process characterization and control.

Sponsor:

Bioengineering

Chair:

Christie A.M. Peebles
Assistant Professor
Colorodo State University
Chemical and Biological Engineering
Fort Collins, CO 80523
Email: christie.peebles@colostate.edu

Co-chairs:

Ganesh Sriram
Assistant Professor
University of Maryland
Chemical and Biomolecular Engineering
1208D Chemical and Nuclear Engr. Bldg. 090
College Park, MD 20742
Email: gsriram@umd.edu

Gargi Ghosh
Assistant Professor
University of Michigan, Dearborn
Mechanical Engineering
4901 Evergreen Road
Dearborn, MI 48128
Email: gargi@umich.edu

Vijayakumar Janakiraman
Senior Engineer
Biogen Idec
Cell Culture Development
5000 Davis Drive
Research Triangle Park, NC 27709
Email: vijay.janakiraman@biogenidec.com

Papers:

75a

Using Atmospheric Carbon Dioxide Environments to Improve Control of Stem Cell Expansions
Sarah W. Harcum, Clemson University; Arthur Nathan Brodsky, Clemson University

75b

Characterizing the Formation of Inverse Solubility Salt Precipitates in Cell Culture Media and Mitigation Strategies During Thermal Treatment for Viral Inactivation
Prince Bhebe, Amgen

75c

Investigation of Process Parameters and Their Effect On Cell Metabolism and N-Linked Glycosylation
Marija Sarenac, Institute of Chemical and Bioengineering, ETH; Miroslav Soos, Institute of Chemical and Bioengineering, ETH; Massimo Morbidelli, Institute of Chemical and Bioengineering, ETH

75d

Application of Multivariate Analysis Tools and Design of Experiments (DoE) to Model the Design Space for Characterization of a Mammalian Cell Culture Process
Vijayakumar Janakiraman, Biogen Idec; Benjamin Orbon, Biogen Idec; Yao-Ming Huang, Biogen Idec; Barry Wolf, Abbott Biotherapeutics Corp.; Maartje Verschuur, Abbott Biotherapeutics Corp.; Amit Varma, Abbott Biotherapeutics Corp.; Marty Sinacore, Biogen Idec; Thomas Ryll, Biogen Idec

Break

75e

Facing Heterogeneities in Bioprocesses, a Downscale Approach Tailored to Suit Large Scale Conditions
Benjamin Neunstoecklin, Institute of Chemical and Bioengineering, ETH; Miroslav Soos, Institute of Chemical and Bioengineering, ETH; Massimo Morbidelli, Institute of Chemical and Bioengineering, ETH

75f

Microfluidic Scale-Down of Upstream Biopharmaceutical Production
Shireen Goh, Massachusetts Institute of Technology ; Michelangelo Canzoneri, Sanofi-Aventis Deutschland GmbH; Horst Blum, Sanofi-Aventis Deutschland GmbH; Rajeev J. Ram, Massachusetts Institute of Technology; Anthony J. Sinskey, MIT

75g

Enhancement of Cell Adhesion and Proliferation Through Surface Roughness Modification in CHO Cell Cultures in PMMA-PDMS Micro-Devices
Lucía D. Garza-García, Tecnológico de Monterrey; Eduardo J. Tapia-Mejía, Tecnológico de Monterrey; Erika García-López, Tecnológico de Monterrey; Sergio Camacho-León, Tecnológico de Monterrey; Ciro Angel Rodríguez-González, Tecnológico de Monterrey; Leydi Maribel Carrillo-Cocom, Tecnológico de Monterrey; Mario M. Alvarez, Tecnológico de Monterrey

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

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