Session: Cell Culture II: Metabolic Flux Analysis and Modeling (2012 Annual Meeting)

Description:

This session intends to cover the state-of-the-art in mammalian, plant, algal and insect cell culture toward the production of biofuels, therapeutics and high-value secondary metabolites. This session will focus on phenotype characterization using metabolic flux analysis and metabolomics, and the development of mathematical models towards prediction and control of cell culture behavior on small and large scales.

Sponsor:

Bioengineering

Chair:

Jamey Young
Vanderbilt University
Chemical and Biomolecular Engineering
2400 Highland Avenue
Nashville, TN 37212
Phone Number: 615-343-4253
Email: j.d.young@vanderbilt.edu

Co-chairs:

Cong Trinh
Assistant Professor
University of Tennessee, Knoxville
Department of Chemical and Biomolecular Engineering
Knoxville, TN 37996
Knoxville, TN 37996
Phone Number: 865-974-8121
Email: ctrinh@utk.edu

Seongkyu Yoon
Assistant Professor
University of Massashusetts
Chemical Engineering
Lowell, MA 01854
Phone Number: 978-934-4741
Fax Number: 978-934-3047
Email: seongkyu_yoon@uml.edu

Papers:

199a

Analysis of Metabolic Flux Rewiring in CHO Cells During Fed-Batch Culture
Maciek R. Antoniewicz, University of Delaware; Woo Suk Ahn, University of Delaware

199b

Quantifying the Impact of Bcl-2Δ Overexpression Upon Central Metabolism Through 13C Metabolic Flux Analysis
Neil Templeton, Vanderbilt University; Abasha Lewis, Johns Hopkins University; Haimanti Dorai, Janssen Pharmaceuticals (J&J); Kevin Smith, Janssen Pharmaceuticals (J&J); Steven Lang, Janssen Pharmaceuticals (J&J); Michael J. Betenbaugh, Johns Hopkins University; Jamey D. Young, Vanderbilt University

199c

An Integrated Modeling and Experimental Framework for Predicting the N-Linked Glycosylation of Monoclonal Antibodies
Ioscani Jimenez del Val, Imperial College London; Cleo Kontoravdi, Imperial College London

199d

A Systems Biology Approach for Mechanistic Understanding of Glycan Structure and Function
Gang Liu, SUNY at Buffalo; Apurv Puri, SUNY at Buffalo; Sriram Neelamegham, SUNY at Buffalo

199e

Development of a Stochastic Model of Heterogeneity of Human Pluripotent Stem Cell Populations Under Conditions Promoting Self-Renewal or Differentiation
Jincheng Wu, State University of New York at Buffalo; Emmanuel S. Tzanakakis, State University of New York at Buffalo

199f

Modeling of Fluorescent Protein-Labeled Cell Populations to Analyze Transcriptional and Division Effects On Fluorescent Intensity Distributions
Loveleena Bansal, Texas A&M University; Shreya Maiti, Texas A&M University; Arul Jayaraman, Texas A&M University; Carl Laird, Texas A&M University; Juergen Hahn, Rensselaer Polytechnic Institute

199g

Analysis of the Effects of Varying Carbon Dioxide Concentration in the Biomass Production and Metabolic Network of the Microalgae Chlamydomonas Reinhardtii
Flavia Vischi Winck, Universidad de los Andes; Rubén Darío Lopez Parra, Universidad de los Andes; Rossmary Jay Pang Moncada, Universidad de los Andes; Diego Mauricio Riaño-Pachón, Universidad de los Andes; Jorge M. Gomez, Universidad de los Andes; Nubia Milena Velasco Rodriguez, Universidad de los Andes; Andrés Fernando González Barrios, Universidad de los Andes

199h

Genome-Scale Flux Balance Analysis of Tree Metabolism
Ashish Misra, University of Maryland; Margaret Simons, University of Maryland; Matthew Conway, University of Maryland; Gary D. Coleman, University of Maryland, College Park; Ganesh Sriram, University of Maryland

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

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