This preliminary program is subject to change.

Biomaterials for Stem Cell Expansion and Differentiation


Description:
Stem cells hold great promise as a tool in regenerative medicine; however, maintaining, expanding, and differentiating stem cells on the scale and with the uniformity necessary for clinical applications is challenging. Biomaterials can assist in overcoming these obstacles. By researching how biomaterials’ physical, chemical, and mechanical properties influence cell phenotype, it is possible to manipulate these properties to guide cell behavior. This session will include studies examining the design and use of biomaterials to direct stem cell behavior, studies investigating changes in phenotype as a result of biomaterial interactions, and studies characterizing biomaterials used in stem cell culture and differentiation.

Sponsor:
Biomaterials


Chair:
Julie C. Liu
Assistant Professor
Purdue University
School of Chemical Engineering
480 Stadium Mall Drive
West Lafayette, IN 47907
Email: julieliu@purdue.edu

Co-Chair:
Brendan A. Harley
University of Illinois at Urbana-Champaign
Chemical & Biomolecular Engineering
Urbana, IL 61801
Phone Number: 217-244-7112
Email: bharley@illinois.edu


Papers:
Amphiphilic Polyanhydride Films Promote Stem Cell Differentiation and Proliferation
Latrisha K. Petersen, Iowa State University; Surya K. Mallapragada, Iowa State University; Donald S. Sakaguchi, Iowa State University; Balaji Narasimhan, Iowa State University
Hydrogels for Controlling Neural Stem Cell Fate Through Intracellular Redox State
Kyle J. Lampe, Stanford University; Sarah C. Heilshorn, Stanford University; Melissa J. Mahoney, University of Colorado
Biomimicry of Cellular Ligand Presentation in 3D Stem Cell Scaffolds Via Proteolipobead-Matrix Hybrid Systems
Eric Fried, City College of New York of CUNY; Michelle Gupta, City College of New York of CUNY; Devika Varma, City College of New York of CUNY; Steve Nicoll, City College of New York of CUNY; M. Lane Gilchrist, City College and the Graduate Center of the City University of New York
Spatially-Patterned Collagen-GAG Scaffolds for Regulating MSC Fate
Steven R. Caliari, University of Illinois at Urbana-Champaign; Daniel W. Weisgerber, University of Illinois at Urbana-Champaign; Douglas O. Kelkhoff, University of Illinois at Urbana-Champaign; Manuel A. Ramirez, University of Illinois at Urbana-Champaign; Brendan A. Harley, University of Illinois at Urbana-Champaign
Protein-Based Biomaterials Containing a BMP Peptide Accelerate Osteogenic Differentiation
Yeji Kim, Purdue University; Julie C. Liu, Purdue University
Stiffening Hydrogels to Probe Stem Cell Response to Dynamic Mechanics
Murat Guvendiren, University of Pennsylvania; Jason A. Burdick, University of Pennsylvania
Substrate Elasticity Regulates the Biophysical Properties and Lineage Commitment of Hematopoietic Stem and Progenitor Cells
Ji Sun Choi, University of Illinois at Urbana-Champaign; Brendan A.C. Harley, University of Illinois at Urbana-Champaign
Alginate Encapsulation of Human Embryonic Stem Cells: Promising Platform for Pancreatic Maturation
Thomas Richardson, University of Pittsburgh; Prashant Kumta, University of Pittsburgh; Ipsita Banerjee, University of Pittsburgh
See more of this Group/Topical: Materials Engineering and Sciences Division