This preliminary program is subject to change.

Synthetic Systems Biology I


Description:
Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest.

Sponsor:
Topical A: Systems Biology


Chair:
Kristala Prather
Massachusetts Institute of Technology
Chemical Engineering
77 Massachusetts Ave Rm 66-425
Cambridge, MA 02139
Phone Number: 617-253-1950
Fax Number: 617-258-5042
Email: kljp@mit.edu

Co-Chair:
Michael C. Jewett
Assistant Professor
Northwestern University
Chemical and Biological Engineering
2145 Sheridan Road
Evanston, IL 60208-3120
Phone Number: (847) 467-5007
Email: m-jewett@northwestern.edu


Papers:
Molecular Crowding Shaping of Gene Expression Dynamics
Cheemeng Tan, Carnegie Mellon University; Saumya Saurabh, Carnegie Mellon University; Marcel Bruchez, Carnegie Mellon University; Philip R. LeDuc, Carnegie Mellon University; Russell Schwartz, Carnegie Mellon University
The Single Cell Distribution of Plasmid Copy Numbers
James Boedicker, Caltech; Franz Weinert, Caltech; Rob Phillips, Caltech
Exploring Bacterial Sugar Consumption At the Single-Cell Level Using An Integrated Computational and Experimental Approach
Konstantinos Biliouris, University of Minnesota; Taliman Afroz, North Carolina State University; Chase L. Beisel, North Carolina State University; Yiannis Kaznessis, University of Minnesota
Investigating Heterogeneous System Performance of Synthetic Myosins Computationally
Paul Egan, Carnegie Mellon University; Jonathan Cagan, Carnegie Mellon University; Christian Schunn, University of Pittsburgh; Philip R. LeDuc, Carnegie Mellon University
Construction of Genetic Programs by Layering Logic Gates in Single Cells
Tae Seok Moon, Washington University in St. Louis; Christopher A. Voigt, Massachusetts Institute of Technology
Engineering TAL Effector Nucleases (TALENs) for Targeted Genome Editing
Ning Sun, University of Illinois at Urbana-Champaign; Jing Liang, University of Illinois at Urbana-Champaign; Zhanar Abil, University of Illinois at Urbana-Champaign; Huimin Zhao, University of Illinois at Urbana-Champaign
See more of this Group/Topical: Topical A: Systems Biology