This preliminary program is subject to change.

Engineered Composite Particulate Systems for Pharmaceutical Active Ingredient Delivery I


Description:
The main objective of this session is to encourage papers and subsequent discussions that lead to development of the scientific foundation for forming building blocks such as particles, suspensions, granules, etc, consisting of pharmaceutical active ingredients with desired properties that improve the final product quality. Presentations dealing with development of science-based methodologies, processes, and formulations for forming materials engineered to have desired properties required for achieving ideal active substance delivery are encouraged. Major topics, include but are not limited to; formation and stabilization of particle suspensions, novel formulations to improve bioavailability of APIs, methods for particle functionalization and surface modification for optimizing and controlling physicochemical properties of materials that impact composite particle system performance.

Sponsor:
Particle Production and Characterization
Co-Sponsor(s):
Pharmaceuticals (15b)


Chair:
Stephen L. Conway
Principal Engineer
Merck & Co., Inc.
Center for Material Science and Engineering
WP75B-210
West Point, PA 19486
Email: stephen_conway@merck.com

Co-chairs:
Rajesh N. Dave
New Jersey Institute of Technology
Chemical Engineering
138 Warren Street, YCEES 208
Newark, NJ 07102
Email: dave@njit.edu

Ilgaz Akseli
Senior Scientist
Boehringer Ingelheim
R&D Pharmaceutical Development
900 Ridgebury Rd
Ridgefield, CT 06877
Phone Number: 203-791-6703
Email: ilgaz.akseli@boehringer-ingelheim.com


Papers:
Relationship Between Solution Metastable Limit and Solubility
Michael Tomasini, Rutgers University; M. Silvina Tomassone, Rutgers University
Measuring the Energetic Heterogeneity of Pharmaceutical Powders and the Effects On Powder Processing and Formulation
Daniel J. Burnett, Surface Measurement Systems; Jiyi Khoo, Surface Measurement Systems
Formation of Itraconazole-Succinic Acid Cocrystals by CO2 Antisolvent Cocrystallization
Courtney A. Ober, Auburn University; Ram B. Gupta, Auburn University
Preparation of Co-Ground Drug-Superdisintegrant Nanosuspensions As a Precursor to the Production of Fast Dissolving Surfactant-Free Nanocomposite Microparticles
Mohammad Azad, New Jersey Institute of Technology; Afolawemi Afolabi, New Jersey Institute of Technology; Rajesh Davé, New Jersey Institute of Technology; Ecevit Bilgili, New Jersey Institute of Technology
Wet-Media Milling of Colloidal Drug Suspensions Stabilized by Means of Charged Nanoparticles
Michael Juhnke, Novartis Pharma AG; Edgar John, Novartis Pharma AG
Interactive Mixtures for Dissolution Rate Enhancement of Cefuroxime Axetil
Namita Dalal, Duquesne University; Ira Shea Buckner, Duquesne University
Formation of Stable Nanocarriers by Tuning Pharmaceutically Active Ingredient Properties Via an in Situ Salt Precipitation
Nathalie M. Pinkerton, Princeton University; Arnaud Grandeury, Novartis Pharma AG; Andreas Fisch, Novartis Pharma AG; Jörg Brozio, Novartis Pharma AG; Bernd Riebesehl, Novartis Pharma AG; Robert K. Prud'homme, Princeton University
See more of this Group/Topical: Particle Technology Forum