Session: Crystallization of Pharmaceutical and Biological Molecules I (2012 Annual Meeting)

Description:

This session welcomes papers addressing fundamental as well as applied studies in the area of crystallization of pharmaceutical or biological molecules. Topics related to experimental studies, theory and simulation that contribute to fundamental understanding of crystallization as well as industrial case studies on the crystallization development of pharmaceutical and biological compounds are encouraged.

Sponsor:

Pharmaceuticals

Co-Sponsor(s):

Crystallization and Evaporation (02B)

Chair:

Shailendra Bordawekar
Abbott Laboratories
Process Research & Development
1401 Sheridan Rd
North Chicago, IL 60048
Phone Number: 847-937-6100
Email: Shailendra.Bordawekar@abbott.com

Co-chairs:

Moiz Diwan
Abbott Laboratories
Global Pharmaceutical Research and Development
1401 Sheridan Drive
North Chicago, IL 60031
Email: Moiz.Diwan@abbott.com

Sarah L. Perry
Graduate Student
University of Illinois at Urbana-Champaign
Department of Chemical & Biomolecular Engineering
600 S. Mathews
Urbana, IL 61801
Email: perrys@uchicago.edu

Papers:

23a

Microstructural Characterization and Dissolution Behavior of Drug/Semicrystalline Polymer Systems On Substrates
Hsin-Yun Hsu, Purdue University; Michael T. Harris, Purdue University

23b

Slurry Crystallization of Water-Insoluble Drug Substance – Overcoming Challenges in Solubility and Miscibility Requirements for Solvents and Anti-Solvents
Alexander Chu-Kung, Abbott Laboratories; Hsien-Hsin Tung, Abbott Laboratories

23c

A Microfluidic Platform for In Meso Crystallization and In Situ Crystal X-Ray Diffraction of Membrane Proteins
Daria S. Khvostichenko, University of Illinois at Urbana-Champaign; Jeremy M. Schieferstein, University of Illinois at Urbana-Champaign; Ashtamurthy Pawate, University of Illinois at Urbana-Champaign; Paul J.A. Kenis, University of Illinois at Urbana-Champaign

23d

Modeling and Simulation of Coaxial Crystallizers by Dynamically Coupled Population Balance, Macromixing, and Micromixing Models
J. Carl Pirkle Jr., Massachusetts Institute of Technology; Lucas Foguth, Massachusetts Institute of Technology; Steven J. Brenek, Pfizer, Inc; Kevin Girard, Pfizer, Inc; Richard D. Braatz, Massachusetts Institute of Technology

23e

Impact of a Reversible Solid State Form Change On Particle Morphology and Bulk Powder Properties of a Pharmaceutical Compound
Joshua D. Engstrom, Bristol-Myers Squibb Company; Qi Gao, Bristol-Myers Squibb Co.; Daniel Roberts, Bristol-Myers Squibb Co.; Chenkou Wei, Bristol-Myers Squibb Co.; Chiajen Lai, Bristol-Myers Squibb Company; Jonathan Brown, Bristol-Myers Squibb Company

23f

The Morphological-Population Balance Model (M-PBM) Generator. Application to Additives Controlled Crystallization of KAP
Meenesh R. Singh, Purdue University; Doraiswami Ramkrishna, Purdue University

See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division - See also TI: Comprehensive Quality by Design in Pharmaceutical Development and Manufacture

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