This preliminary program is subject to change.

Synthetic Systems Biology II


Description:
Systems biology is the study of whole biological ensembles, rather than isolated parts, in order to build a predictive biological understanding of a defined system’s behavior. Synthetic biology has been defined as the design and construction of systems that exhibit complex dynamical or logical behavior. The intersection between these two fields is likely to significantly enhance efforts in design-based biological engineering and therefore greatly increase human capability. This session will cover current applications of systems biology theory and techniques to aid in the design of synthetic biological systems. In addition, efforts that apply synthetic biology research as new tools to expand systems-level understanding or as new concepts in systems biology are of interest.

Sponsor:
Topical A: Systems Biology


Chair:
Michael C. Jewett
Assistant Professor
Northwestern University
Chemical and Biological Engineering
2145 Sheridan Road
Evanston, IL 60208-3120
Phone Number: (847) 467-5007
Email: m-jewett@northwestern.edu

Co-Chair:
Kristala Prather
Massachusetts Institute of Technology
Chemical Engineering
77 Massachusetts Ave Rm 66-425
Cambridge, MA 02139
Phone Number: 617-253-1950
Fax Number: 617-258-5042
Email: kljp@mit.edu


Papers:
Multiplex Recombineering-Enabled Genome Editing Tools
Nanette R. Boyle, University of Colorado at Boulder; Sean A. Lynch, University of Colorado at Boulder; Thomas J. Mansell, University of Colorado at Boulder; Ryan T. Gill, University of Colorado at Boulder
Elucidating the Genetic Architecture of Isobutanol Tolerance in Escherichia Coli Through Targeted Genome Engineering and High Throughput Screening
Jeremy J. Minty, University of Michigan; Jihyang Park, University of Michigan; Lawrence Lai, University of Michigan; Ted A. Zaroff III, University of Michigan; Brian N. Johnson, University of Michigan; Mark A. Burns, University of Michigan; Harris Wang, Harvard University; George M. Church, Harvard Medical School; Xiaoxia Lin, University of Michigan
Towards a Semi-Synthetic Stress Response System to Engineer Solvent Tolerance
Kyle Zingaro, University of Delaware; Eleftherios T. Papoutsakis, Delaware Biotechnology Institute
Improvement of D-Glucaric Acid Production From a Synthetic Pathway in Escherichia Coli
Eric Shiue, Massachusetts Institute of Technology; Kristala Jones Prather, Massachusetts Institute of Technology
Integrating Systems and Synthetic Biology for Engineering Chemical Production in Bacteria
Rebecca M. Lennen, University of Wisconsin-Madison; Brian F. Pfleger, University of Wisconsin Madison
Repressor-Based Tools for Cell-Cell Communication in Synthetic Biology
Jasmine Shong, Rensselaer Polytechnic Institute; Cynthia H. Collins, Rensselaer Polytechnic Institute
A Platform for Synthetic, Orthogonal, Intercellular Communication Via Synthetikines
Rachel M. Dudek, Northwestern University; Nichole Daringer, Northwestern University; Joshua N. Leonard, Northwestern University
Refactoring the Partial Photosynthesis Gene Cluster for the Biosynthesis of the Key Pigment, Bacteriochlorophyll a
Hui Zhou, Massachusetts Institute of Technology; J. Thomas Beatty, University of British Columbia; Christopher A. Voigt, Massachusetts Institute of Technology
See more of this Group/Topical: Topical A: Systems Biology