606 Crystallization of Pharmaceutical and Biological Molecules II

Description:
This session welcomes papers addressing fundamental as well as applied studies in the area of crystallization of pharmaceutical or biological molecules. Topics related to experimental studies, theory and simulation that contribute to fundamental understanding of crystallization as well as industrial case studies on the crystallization development of pharmaceutical and biological compounds are encouraged.

Sponsor:
Crystallization and Evaporation
Co-Sponsor(s):
Pharmaceutical Discovery, Development and Manufacturing Forum (26)

Chair:
Sarah L. Perry
Email: perrys@uchicago.edu

Co-chairs:
Seth Huggins
Email: shuggins@amgen.com

Ryan C. Snyder
Email: ryan.snyder@bucknell.edu


Papers:

8:30 AM
(606a) High-Throughput Membrane Protein Crystallization Condition Screening Using X-Ray Transparent In Meso Microfluidic Chips
Jeremy M. Schieferstein, Daria S. Khvostichenko, Ashtamurthy S. Pawate and Paul J.A. Kenis

8:55 AM
(606b) Solvent Effect On Crystal Morphology: A Hybrid Approach of a Mechanistic Model and Molecular Dynamics
Seung Ha Kim and Michael F. Doherty

9:20 AM
(606c) The Understanding of Nucleation Aspects of Tolbutamide Polymorphs in Solution
Yin Yani, Pui Shan Chow and Reginald Tan

9:45 AM
(606d) Predicting Protein Solubility and Crystallization Behavior Based On the Second Osmotic Virial Coefficient
Christoph Brandenbusch, Marcel Herhut and Gabriele Sadowski

10:10 AM
(606e) Conversion of FBRM® CLD Data to Psd Data: Application to a Needle-Shaped Industrial Case, for the Estimation of Crystallization Kinetics
Niall Mitchell, Bing-Shiou Yang, Sean K. Bermingham, Soojin Kim and Hassan Mumtaz
File available
10:35 AM
(606f) Problematic Crystal Shapes - Causality and Solvent Selection Guidance Based On Periodic Bond Chain Diagrams
Michael A. Lovette
See more of this Group/Topical: Separations Division
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