458 Omics in Biopharmaceutical Bioprocessing

Wednesday, November 19, 2014: 8:30 AM
206 (Hilton Atlanta)
Description:
The applications of the advanced Omics in cell engineering, clone evaluation, feeding strategy development, medium and feed development, bioreactor process parameter optimization, and quality control in manufacturing will be highlighted. The advanced Omics technologies, including genomics, transcriptomics, proteomics, metabolomics, and other Omics analysis,will be considered in this session.

Sponsor:
Pharmaceuticals

Chair:
Margaret Liu
Email: mliu@eng.ua.edu

Co-Chair:
Jianxin Sun
Email: sun187osu@gmail.com


8:30 AM
(458a) Transcriptome of CHO Cells Producers of Recombinant Tpa Cultured Under Moderate Hypothermia
Andrea Bedoya-López, Karel Estrada, Alejandro Sanchez-Flores, Octavio T. Ramírez, Claudia Altamirano, Mauricio Trujillo-Roldán and Norma Valdez-Cruz

8:50 AM
(458b) A System Identification Based Approach for Phenotype Phase Plane Analysis
Andrew Damiani, Q. Peter He and Jin Wang

9:10 AM
(458c) Characterization of Protein Expression Regulators in Different CHO Hosts By Global Proteomics Analysis
Ningning Xu and Margaret Liu

9:30 AM
(458d) Strategic Genome Design to Improve Bioseparation
Bob Beitle, Ellen M. Brune, McKinzie Fruchtl, Ralph Henry and Mohammad M. Ataai

9:50 AM
(458e) Transcriptomic Analysis of Clonal Variation in Pichia Pastoris
Rochelle Aw, Geraint Barton, David J. Leak and Karen M. Polizzi

10:10 AM
(458f) Addressing the Need for a Model Selection Framework in Systems Biology Using Information Theory
Frank T. DeVilbiss, Maxim Raginsky and Doraiswami Ramkrishna

10:30 AM
(458g) Serum-Free Medium Adaptation of Chinese Hamster Ovary (CHO) Cell Lines: A Transcriptome Analysis Using RNA-Seq
Yogender Kumar Gowtham, Sarah W. Harcum and Christopher A Saski

10:50 AM
(458h) An Optimization-Based Feature Selection Methodology for the Discovery of Biomarkers from High-Dimensional Data in Clinical Applications
Yannis A. Guzman, Devaraj Jayachandran, Doraiswami Ramkrishna and Christodoulos A. Floudas
See more of this Group/Topical: Food, Pharmaceutical & Bioengineering Division
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