Kinetic Study of Reactions of Aniline and Benzoyl Chloride in a Microstructured Chemical System

Kinetic Study of Reactions of Aniline and Benzoyl Chloride in a Microstructured Chemical System

Peijian Wang, Kai Wang, Jisong Zhang, Guangsheng Luo^*

The State Key Laboratory of Chemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, China

Abstract

The reaction between aniline and benzoyl chloride is well known for producing high performance polymers and chemicals. But the fast main reaction and reversible consecutive side reaction make process rather complicated and no thorough kinetics study has ever been reported before. A microstructured chemical system, consisting of a micromixer, pre-heat exchange coiled capillaries, a delay loop and a microhydrolyzer, was designed to carry out this reaction in this study using NMP as the solvent. A kinetic model was established, and the values of kinetic constants, pre-exponential factors and activation energies of each reaction as well as their confidence intervals were acquired. With this model each substance concentration versus residence time were obtained to help understand reaction process and further optimize operating conditions. Compared to earlier reports on this reaction, this microstructured chemical system provides more accurate parameters and can develop a reliable platform for kinetic study of similar chemical reactions.

Keywords: kinetics; aniline; benzoyl chloride; NMP; microstructured chemical

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Correspondence concerning this article should be addressed to Prof. Guangsheng Luo at gsluo@tsinghua.edu.cn