487 Mixing Scale-Up/Scale-Down Issues in Pharmaceutical and Biopharmaceuticals Processes

Wednesday, November 16, 2016: 8:30 AM - 11:00 AM
Union Square 1 & 2 (Hilton San Francisco Union Square)
Description:
Mixing Issues and Scale-up/Scale-Down Strategies for the Production of Pharmaceutical and Biopharmaceuticals

Sponsor:
North American Mixing Forum
Co-Sponsor(s):
Pharmaceutical Discovery, Development and Manufacturing Forum (26)

Chair:
Piero M. Armenante
Email: piero.armenante@njit.edu

Co-chairs:
Luis Sierra
Email: luis_sierra2@merck.com

Amanda M. Lewis
Email: amanda.lewis@bms.com


8:30 AM
(487a) Evaluating Mixing Performance in a Stirred Tank Reactor with Different Impeller Geometries and Reactor Size By CFD
Rui C. Silva, Filipe A.P. Ataíde and José L.C. Santos

8:52 AM
(487b) CFD Simulation on Assessment of Biologic Product Mixing Performance in Single Use Technology
Wei Chen, Chris Lee, Rao Mantri and Howard Stamato

9:14 AM
(487c) Characterization of Lab and Plant Reactors Using Fast Competitive Reactions and a Predictive Model
Joe Hannon, Andrew Bird and Andrew Derrick

9:36 AM
(487d) Computational and Experimental Determination of the Hydrodynamics in a Scaled-Down Pharmaceutical Vessel Provided with Angle-Mounted Impellers
Ji Ma and Piero M. Armenante

9:58 AM
(487e) Experimental Study of Wet Milling in a Rotor-Stator Mixer
Richard V. Calabrese and Kanan Ghaderzadeh

10:20 AM
(487f) Practical Large Eddy Simulation
John A. Thomas and Kevin Smith

10:42 AM
(487g) Scale-up Rules for the Generation of Solid-Stabilized Emulsions
Alexandre Al-Haiek, Emir Tsabet and Louis Fradette
See more of this Group/Topical: North American Mixing Forum
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