492888 Graphene Oxide/Lipid Composite Material Towards a Multifunctional Drug Delivery Vehicle

Mohammad Shahadat Hussain Sarkar1, Md. Alamin Miraz1, Ashiqur Rahman2, Yang Lu3, Vu Phan1, Clayton S Jeffryes2 and Evan K. Wujcik3, (1)Dan F. Smith Department of Chemical Engineering, Lamar University, Beaumont, TX, (2)Nanobiomaterials and Bioprocessing Laboratory (NABLAB), Dan F. Smith Department of Chemical Engineering, Lamar University, Beaumont, TX, (3)Materials Engineering And Nanosensor [MEAN] Laboratory, Department of Chemical and Biological Engineering, The University of Alabama, Tuscaloosa, AL

A graphene oxide [GO]/lipid composite for an enhanced and multifunctional drug delivery vehicle has been devised. In this study, liposomes were prepared using the gentle hydration method and integrated with GO, to advance the loading of payloads via noncovalent bonding—so as not to deform the confirmation of the bound molecule. Fluorescent integration of the liposome and GO was analyzed and monitored under light microscopy and UV-vis spectroscopy. This work can also be extended to theranostic processes, such as detection and delivery schemes.

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See more of this Session: 2D Nanocomposites: New Composites with 2-Dimensional Nanomaterials
See more of this Group/Topical: Materials Engineering and Sciences Division