16 Biomaterials for Nucleic Acid Delivery


Description:
This session will cover novel design principles that govern biomaterial design and evaluation for nucleic delivery applications with particular focus on how biomaterial properties (e.g. mechanical properties, chemical composition, degradation kinetics, micro/nano-structure, etc.) influence the delivery efficiency. Possible topics include, but are not limited to design of novel vehicles for nucleic acid delivery, stimuli-sensitive or targeted delivery, enhancement of delivery/transfection efficiency via specific biomaterial properties and the influence of biomaterial properties on intracellular trafficking and/or transport of nucleic acids. Graduate Students: By applying to this session you may be eligible for the Biomaterials Graduate Student Award Session established to honor the best graduate student submissions through recognition and cash awards. See the session titled “Biomaterials: Graduate Student Award Session” for details.

Sponsor:
Biomaterials
Co-Sponsor(s):
Engineering Fundamentals in Life Science (15D), Bionanotechnology (22B)


Chair:
Millicent Sullivan
Assistant Professor
University of Delaware
Chemical Engineering
150 Academy Street
Newark, DE
19716
Fax Number: 302-831-3009
Email: msulliva@udel.edu

Co-chairs:
John Wilson
Assistant Professor
Vanderbilt University
Chemical and Biomolecular Engineering
Nashville, TN
37212
Email: john.t.wilson@vanderbilt.edu

Christopher A. Alabi
Assistant Professor
Cornell University
Chemical and Biomolecular Engineering
120 Olin Hall
Ithaca, NY
14853
Email: caa238@cornell.edu


Papers:
16a
Lipid-like Materials for RNA Delivery: A How-to Guide for Hacking Gene Expression
Kathryn A. Whitehead, Carnegie Mellon University
16b
Triple Delivery Nanoscale Device for siRNA, Vismodegib and Gemcitabine Co-Delivery to Treat Pancreatic Cancer
Metin Uz, Iowa State University; Satyanarayana Rachagani, University of Nebraska Medical Center; Surinder Batra, University of Nebraska Medical Center; Surya K. Mallapragada, Iowa State University
16c
Influence of Dextran and Surface Charge on Nanoparticle-Mediated siRNA Delivery
Daniel Vocelle, Michigan State University; Olivia Chesniak, Michigan State University; Mitch Smith, Michigan State University; Christina Chan, Michigan State Uiversity; S. Patrick Walton, Michigan State University
16d
Peg-Poly(beta-amino ester) Delivery Systems for Periodic shRNA
Connie Wu, MIT; Jiahe Li, Massachusetts Institute of Technology; Wade Wang, Massachusetts Institute of Technology; Paula T. Hammond, MIT
16e
Structurally Programmed Assembly of Ribonucleoproteins for Superior mRNA Delivery
Jiahe Li, Massachusetts Institute of Technology; Wade Wang, MIT; Yanpu He, MIT; Yingzhong Li, MIT; Darrell J. Irvine, MIT; Paula T. Hammond, MIT
16f
Cationic Peptide Amphiphile Micelles(PAMs) As Nucleic Acid Based Adjuvants Carriers for the Improvement of Subunit Vaccine Efficiency
Rui Zhang, University of Missouri; Josiah Smith, University of Missouri; Jake Kramer, University of Missouri-Columbia; Logan Morton, University of Missouri; Brittany Allen, University of Missouri; Caitlin Leeper, University of Missouri-Columbia; Xiaolei Li, University of Missouri-Columbia; Fabio Gallazzi, University of Missouri; Tommi White, University of Missouri; Bret Ulery, University of Missouri
Abstract Submissions Closed
See more of this Group/Topical: Materials Engineering and Sciences Division
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